Results 161 to 170 of about 154,811 (301)

A Hybrid Magnetic Actuation System for Single‐Input Multistates Stabilization: Application to pH‐Responsive Drug Delivery

open access: yesAdvanced Intelligent Systems, EarlyView.
This study presents an integrated proof‐of‐concept robotic platform for targeted delivery applications. A hybrid magnetic actuation system achieves single‐input (z) multistate stabilization (x, y, ϕ, and θ) for precise capsule transport with submillimeter positioning accuracy.
Sejun Park   +6 more
wiley   +1 more source

Cobalt‐Catalyzed C─N Bond Formation via Metal‐Hydride Hydrogen Atom Transfer (MHAT)

open access: yesAngewandte Chemie, EarlyView.
Cobalt‐catalyzed metal‐hydride hydrogen atom transfer (Co‐MHAT) converts simple alkenes into C─N bonds under mild, near‐neutral conditions. A shared Co─H‐initiated radical/organocobalt intermediate is channeled into radical trapping, radical‐polar crossover, or radical ligand transfer, unifying hydroamination, hydroazidation, hydroamidation, and remote
Arman Khosravi, Ming‐Yu Ngai
wiley   +2 more sources

Integration of Liquid Handling Robotics, Turbidimetry, and Machine Learning Toward Inverse Design of Lower Critical Solution Temperature Polymer Formulations

open access: yesAdvanced Intelligent Systems, EarlyView.
An integrated OT‐2/plate reader platform automates LCST cloud point measurement of NIPAM‐co‐DMAEMA copolymers across high‐dimensional formulation spaces. Machine learning trained on the resulting high‐throughput datasets achieves R2 up to 0.96 and enables inverse design of polymer formulations to target transition temperatures with <1% error.
Lachlan Alexander   +2 more
wiley   +1 more source

Beyond the Camera: Epidermal Sensor Platforms for Intelligent Facial Expression Recognition and Interactive Human Monitoring

open access: yesAdvanced Intelligent Systems, EarlyView.
Skin‐conformal epidermal sensors enable camera‐free intelligent facial monitoring by converting facial deformation and muscle activity into electrical signals through piezoresistive, capacitive, electrophysiologic, and self‐powered mechanisms. Coupled with artificial intelligence (AI), these platforms support facial expression recognition, human ...
Jeehyun Joung   +5 more
wiley   +1 more source

Bromide‐Activated Four‐Electron Iodine Chemistry Enabled by a Pyridinium‐Integrated Hydrogel Electrolyte

open access: yesAngewandte Chemie, EarlyView.
An experimental–computational framework links I‐X bond polarization and the hydrolytic stability of IX2− intermediates. Guided by this insight, PyBr is introduced as a functional bromide source to activate highly reversible I0/I+ chemistry and integrated with a zincophilic sulfonate‐rich hydrogel. This design enables 20 000 stable cycles in a coin cell
Rujiao Ma   +5 more
wiley   +2 more sources

Functional Specialization of Respiratory and Olfactory Mucus Revealed by Proteomic Profiling

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Mucus overlies the nasal mucosa in the respiratory and olfactory regions, which perform distinct physiological functions. However, proteomic differences between respiratory mucosa (RM) and olfactory cleft (OC) mucus remain unclear.
Anna Kristina Hernandez   +7 more
wiley   +1 more source

Downsizing Electrophilic MAX‐Derived Helical Zipper Peptides to Covalently Bind and Degrade Oncogenic MYC

open access: yesAngewandte Chemie, EarlyView.
Oncogenic MYC is a transcription factor that is difficult to inhibit. However, precise positioning of an acrylamide electrophile in MAX to covalently bond to the unique Cys438 in MYC, enabled shortening and optimizing of MAX‐derived, helix‐constrained peptides with high‐affinity and selectivity.
Aline Dantas de Araujo   +7 more
wiley   +2 more sources

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