Results 41 to 50 of about 213,915 (375)

Treatment with Repository Corticotropin Injection in Patients with Rheumatoid Arthritis, Systemic Lupus Erythematosus, and Dermatomyositis/Polymyositis

open access: yesOpen Access Rheumatology: Research and Reviews, 2020
Nancy Ho-Mahler,1 Beni Turner,2 Michael Eaddy,2 Mark L Hanke,1 Winnie W Nelson1 1Mallinckrodt Pharmaceuticals, Bedminster, NJ, USA; 2Xcenda, Palm Harbor, FL, USACorrespondence: Nancy Ho-MahlerMallinckrodt Pharmaceuticals, 1425 U.S. Route 206, Bedminster,
Ho-Mahler N   +4 more
doaj  

Lean Cushing's

open access: yesJournal of Family Medicine and Primary Care, 2020
This is a case report of 59 years old male with adrenocorticotropic hormone ACTH-independent macronodular adrenal hyperplasia (AIMAH), which is a rare cause of Cushing's syndrome. He was detected to have adrenal lesions incidentally on imaging.
Yashendu Sarda   +4 more
doaj   +1 more source

The Influence of Hyperactivity of the Hypothalamic-pituitary-adrenal Axis and Hyperglycemia on the 5-HT2A Receptor-mediated Wet-dog Shake Responses in Rats [PDF]

open access: yes, 2007
Hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis induces hyperglycemia and serotonin (5-HT)2A receptor supersensitivity. In the present study, to investigate the effect of hyperglycemia on the function of 5-HT2A receptors, we compared the 5-
Amano, Manabu   +7 more
core   +1 more source

Developmental Outcomes of Infants Treated With Combination Therapy for Infantile Spasms

open access: yesPediatric Neurology Briefs, 2019
The International Collaborative Infantile Spasms Study (ICISS) Group evaluated the developmental and epilepsy outcomes at 18 months following hormonal treatment alone or hormonal treatment combined with vigabatrin.
Jacqueline Wolak, Sunita N Misra
doaj   +1 more source

A case of cushing syndrome of undetermined cause managed medically with cabergoline

open access: yesSri Lanka Journal of Medicine, 2018
We report a 77 year old lady with hypertension and hypokalaemic metabolic alkalosis who was found to have ACTH dependant Cushing Syndrome (CS). Cortisol level was not suppressed during low dose as well as high dose dexamethazone suppression test (HDDST).
Muneer Ahmad   +1 more
doaj   +1 more source

Nitric oxide donation lowers blood pressure in adrenocorticotrophic hormone-induced hypertensive rats.

open access: yes, 2004
Adrenocorticotrophic hormone (ACTH) elevates systolic blood pressure (SBP) and lowers plasma reactive nitrogen intermediates in rats. We assessed the ability of NO donation from isosorbide dinitrate (ISDN) to prevent or reverse the hypertension caused by
Andrews, Miles C   +4 more
core   +1 more source

The melanocortin receptors and their accessory proteins. [PDF]

open access: yes, 2013
The five melanocortin receptors (MCRs) named MC1R-MC5R have diverse physiological roles encompassing pigmentation, steroidogenesis, energy homeostasis and feeding behavior as well as exocrine function.
Chan, LF   +3 more
core   +2 more sources

Sex Hormones Associate With Amyotrophic Lateral Sclerosis Risk and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) risk differs by sex and age, implicating sex hormones as potential modifiers. This study examined plasma levels of biologically active sex hormones and their association with ALS odds and survival in cases (females n = 131, males n = 189) and controls (females n = 138, males n = 150) from the University of ...
Stephen A. Goutman   +5 more
wiley   +1 more source

Corticotropinoma as a Component of Carney Complex. [PDF]

open access: yes, 2017
Known germline gene abnormalities cause one-fifth of the pituitary adenomas in children and adolescents, but, in contrast with other pituitary tumor types, the genetic causes of corticotropinomas are largely unknown.
Chittiboina, Prashant   +11 more
core   +2 more sources

Immune checkpoint inhibitor induced hypophysitis: a specific disease of corticotrophs?

open access: yesEndocrine Connections
Introduction: The aim of this study was to define functional and anatomical pituitary disease at the time of presentation following immune checkpoint inhibitor (ICI) therapy and to describe any changes in pituitary function over time.
Nishchil Patel   +6 more
doaj   +1 more source

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