Cardiomyopathy-associated and basic residue mutations in myopalladin alter actin binding, bundling, and structural stability. [PDF]
Arachchige AR +8 more
europepmc +1 more source
Proteins, Processing, and Properties of Adhesive Fluid Condensates Purified from Mussels
Mussels exhibit an unmatched proficiency for adhering to wet surfaces in salty environments—a remarkable ability that could inspire new biomedical and technical glues. The fluid protein condensates used to form the underwater mussel glue are extracted, reconstituted and characterized with advanced spectroscopy and nanomechanical analysis, revealing ...
Mathieu D. Rivard +8 more
wiley +1 more source
The Nemp1-Nesprin complex mediates cellular responses to matrix mechanics. [PDF]
Ganguly A +13 more
europepmc +1 more source
Controlling 3D Contractility via Engineered Fibrous Hydrogel Composites
A tunable composite contractile assembly (CCA) is developed that can permit or resist contraction without changing cell‐adhesion and density, unlike collagen whose inherent coupling of these ECM cues limits its use as a platform in contractility studies.
Karen L. Xu +7 more
wiley +1 more source
Correction: Actin arginylation alters myosin engagement and F-actin patterning despite structural conservation. [PDF]
Pinto CS +10 more
europepmc +1 more source
Herein, an RBC membrane‐derived nanoparticle (CMN‐ICG) is engineered to efficiently deliver a sonosensitizing agent, indocyanine green (ICG), for sonotherapy of hepatocellular carcinoma (HCC). CMN‐ICG exhibits excellent cytocompatibility, significantly enhances hepatocyte uptake, and produces excessive reactive oxygen species (ROS) upon ultrasound ...
Alap Ali Zahid +6 more
wiley +1 more source
The actin cytoskeleton is required to maintain plant cell division orientation against cellular geometry. [PDF]
Goldy C +11 more
europepmc +1 more source
Cardiac‐Derived ECM Microspheres for Enhanced hiPSC‐CMs Maturation
Cardiac extracellular matrix microspheres derived from decellularized porcine heart provide a biomimetic 3D microenvironment for human induced pluripotent stem cell–derived cardiomyocytes (hiPSC‐CMs). This platform supports short‐ and long‐term culture, enhances structural organization, and promotes electrophysiological and functional maturation of ...
Jiazhu Xu +9 more
wiley +1 more source
Elucidating chiral myosin-induced actin dynamics: From single-filament behavior to collective structures. [PDF]
Haraguchi T +9 more
europepmc +1 more source
3D‐Printed Porous Hydroxyapatite Formed via Enzymatic Mineralization
Bone combines lightness, strength, and the ability to heal, inspiring new materials design. This work introduces a room‐temperature, enzyme‐mediated 3D printing method to create porous hydroxyapatite scaffolds. The process avoids energy‐intensive sintering, preserves bioactivity, and allows control over porosity and mineralization.
Francesca Bono +6 more
wiley +1 more source

