Results 141 to 150 of about 1,498,374 (404)
Molecular mechanisms of the regulation of ATPase cycle in striated muscle [PDF]
, 2007 New data on the molecular mechanism of the regulation of ATPase cycle by troponin-tropomyosin system have been obtained in reconstructed muscle fibers by using the polarized fluorescence technique, which allowed us following the azimuthal movements of ...
Charles S. Redwood +2 more
core +1 more source
The role of actin, fimbrin and endocytosis in growth of hyphae in Aspergillus nidulans [PDF]
, 2008 Srijana Upadhyay, Brian D. Shaw
openalex +1 more source
Nuclear F-actin Formation and Reorganization upon Cell Spreading*♦
Journal of Biological Chemistry, 2015 Background: Nuclear actin dynamics may function during basic cellular processes such as adhesion, differentiation, cell shape, and motility. Results: Integrin signaling induces nuclear actin polymerization via the LINC complex in response to fibronectin ...
Matthias Plessner +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
eLife, 2015 Actin filaments assemble inside the nucleus in response to multiple cellular perturbations, including heat shock, protein misfolding, integrin engagement, and serum stimulation. We find that DNA damage also generates nuclear actin filaments—detectable by
Brittany J. Belin, Terri Lee, R. Mullins
semanticscholar +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Friend or Foe: The Role of the Cytoskeleton in Influenza A Virus Assembly
Viruses, 2019 Influenza A Virus (IAV) is a respiratory virus that causes seasonal outbreaks annually and pandemics occasionally. The main targets of the virus are epithelial cells in the respiratory tract.
Sukhmani Bedi, Akira Ono
doaj +1 more source
Polarity sorting drives remodeling of actin-myosin networks [PDF]
, 2018 Viktoria Wollrab +5 more
openalex +1 more source
The centrosome is an actin-organizing center
Nature Cell Biology, 2015 Microtubules and actin filaments are the two main cytoskeleton networks supporting intracellular architecture and cell polarity. The centrosome nucleates and anchors microtubules and is therefore considered to be the main microtubule-organizing centre ...
F. Farina +6 more
semanticscholar +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source