Results 311 to 320 of about 1,498,374 (404)

Interconnected Porous Hydrogels with Tunable Anisotropy Through Aqueous Emulsion Bioprinting

Advanced Functional Materials, EarlyView.
A 3D bioprintable microporous bioink is developed using an aqueous two‐phase system (ATPS) composed of extracellular matrix (ECM) mimetic biopolymers. The ATPS bioink enables the fabrication of interconnected porous architectures with up to 70% porosity, supporting long‐term cell viability and 3D cell alignment, enabling a simultaneous generation of ...
Hugo Edgar‐Vilar, Francisca P. Correia, Inês M. Freitas, Vítor M. Gaspar, João F. Mano   +4 more
wiley   +1 more source

Actin depolymerization by Latrunculin B can either suppress or promote root gravitropism, depending on the developmental stages in Arabidopsis. [PDF]

Plant Signal Behav
Chen A, Wang Q, Sheng X.
europepmc   +1 more source

Proteins, Processing, and Properties of Adhesive Fluid Condensates Purified from Mussels

Advanced Functional Materials, EarlyView.
Mussels exhibit an unmatched proficiency for adhering to wet surfaces in salty environments—a remarkable ability that could inspire new biomedical and technical glues. The fluid protein condensates used to form the underwater mussel glue are extracted, reconstituted and characterized with advanced spectroscopy and nanomechanical analysis, revealing ...
Mathieu D. Rivard, Max Renner‐Rao, Nahid Hassanpour, Franziska Jehle, Chang‐Sheng Wang, Duy Anh Pham, Daniel J. Jackson, Xavier Banquy, Matthew J. Harrington   +8 more
wiley   +1 more source

Endophilin-lamellipodin-VASP, key components in fast endophilin-mediated endocytosis, control actin polymerization within liquid-like condensates. [PDF]

J Biol Chem
Narayan KB, James HP, Cope J, Mondal S, Baeyens L, Milano F, Zheng J, Krause M, Baumgart T.   +8 more
europepmc   +1 more source

Gold Nanoclusters as Dual Agents for Engineering Tumor Vascular Leakiness and Performing Photothermal Therapy

Advanced Functional Materials, EarlyView.
Many cancer nanotherapeutics, while potent, suffer from the inability to escape from the tumor vasculature, especially in the absence of endothelial permeability. In this work, ultrasmall gold nanoclusters could engineer nanomaterials induced endothelial leakiness (NanoEL) and harness strong NIR induced photothermal characteristics to suppress tumor ...
Nengyi Ni, Kuoran Xing, Bihan Zhang, Baoteng Wang, Yinglu Chen, Jianping Xie, Xiao Sun, Jinping Wang, David Tai Leong   +8 more
wiley   +1 more source

Actomyosin contractility and a threshold of cadherin cell adhesion are required during tissue fusion. [PDF]

J Cell Biol
Teng CS, Curtis SW, Brewer GC, Leslie-Clarkson EJ, Bush JO.   +4 more
europepmc   +1 more source

Cell Surface Thiol Engineering Mechanoregulates Myogenic Differentiation via the FAK–PI3K–AKT Axis

Advanced Healthcare Materials, EarlyView.
Schematic diagram illustrating how cell surface modification of skeletal muscle progenitor cells through TCEP treatment reveals enhanced cell adhesion, intracellular tension, and myogenesis at 19.66 kPa stiffness, leading to optimal cell fusion. In contrast, no significant changes are observed in the softer (10.61 kPa) or stiffer (49.4 kPa) matrices ...
Juyeon Kim, Sung Sik Hur, Jae Hong Park, Myung Jin Ban, Jin‐Young Kim, Joo Hyun Kim, Ji Hyae Choo, Hae‐Won Kim, Ju Hun Lee, Man Ryul Lee, Yongsung Hwang   +10 more
wiley   +1 more source

SiR-XActin: A Fluorescent Probe for Imaging Actin Dynamics in Live Cells. [PDF]

Angew Chem Int Ed Engl
Nasufovic V, Kompa J, Lindamood HL, Blümke M, Dibsy R, Koch B, Levario-Diaz V, Weber K, Maager M, Nomerotskaia E, Echard A, Cavalcanti-Adam EA, Vitriol EA, Arndt HD, Johnsson K.   +14 more
europepmc   +1 more source

Bone‐Derived dECM Hydrogels Support Tunable Microenvironments for In Vitro Osteogenic Differentiation

Advanced Healthcare Materials, EarlyView.
A tunable methacrylated decellularized bone matrix hydrogel (dECM‐MA) is developed to support 3D culture of human osteoblasts. The hydrogel preserves bone‐specific ECM cues and allows precise control over mechanical properties. This system provides a customizable platform for studying osteogenic differentiation and modeling bone tissue environments for
Minne Dekker, Luke Hipwood, Akhilandeshwari Ravichandran, Dietmar W. Hutmacher, Christoph Meinert, Jacqui McGovern   +5 more
wiley   +1 more source

Targeting leukemic stem cell biomechanics suppresses stemness and enhances NK cell-mediated immunotherapy. [PDF]

Nat Commun
Zhu M, Yang H, Qiu K, Huang B, Liang T, Wang Y, Li H, Wu M, Liu X, Zhao N, Song X, Zhao X, Gao M, Zhao Y, He X, Zhao R, Qian L, Liu Q, Zheng C, Zhu X, Jiang H, Ni F.   +21 more
europepmc   +1 more source