Results 311 to 320 of about 976,237 (341)
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Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase.
Science, 1999The actin cytoskeleton undergoes extensive remodeling during cell morphogenesis and motility. The small guanosine triphosphatase Rho regulates such remodeling, but the underlying mechanisms of this regulation remain unclear.
M. Maekawa +9 more
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Actin-actin binding protein interfaces
Seminars in Cell Biology, 1994The recent elucidation of the three-dimensional structure of gelsolin segment 1 and profilin provides new insights on how these proteins recognize actin. Although the picture is still incomplete and not all biochemical data are consolidated, the results offer clues on how these proteins exert their effect on actin and how they may modulate the ...
Joël Vandekerckhove, Christophe Ampe
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Molecular mechanisms controlling actin filament dynamics in nonmuscle cells.
Annual Review of Biophysics and Biomolecular Structure, 2000We review how motile cells regulate actin filament assembly at their leading edge. Activation of cell surface receptors generates signals (including activated Rho family GTPases) that converge on integrating proteins of the WASp family (WASp, N-WASP, and
T. Pollard, L. Blanchoin, R. Mullins
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The FASEB Journal, 1995
X-ray structure analysis of actin and of the NH2-terminal domain of the heat-shock cognate protein Hsc70 has revealed an unexpected extensive structural similarity between these two molecules. Despite the absence of significant similarity of their amino acid sequences, both proteins share the same core architecture and a common nucleotide binding site ...
Kabsch, W., Holmes, K.
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X-ray structure analysis of actin and of the NH2-terminal domain of the heat-shock cognate protein Hsc70 has revealed an unexpected extensive structural similarity between these two molecules. Despite the absence of significant similarity of their amino acid sequences, both proteins share the same core architecture and a common nucleotide binding site ...
Kabsch, W., Holmes, K.
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Structure of the actin-myosin complex and its implications for muscle contraction.
Science, 1993Muscle contraction consists of a cyclical interaction between myosin and actin driven by the concomitant hydrolysis of adenosine triphosphate (ATP). A model for the rigor complex of F actin and the myosin head was obtained by combining the molecular ...
I. Rayment +6 more
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Journal of Muscle Research and Cell Motility, 1983
Actin filaments can assemble at the barbed end and disassemble simultaneously at the pointed end. A higher monomer concentration is required to balance the association of actin monomers and the dissociation of filament subunits at the pointed end than at the barbed end.
Jean-Marc Neuhaus +3 more
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Actin filaments can assemble at the barbed end and disassemble simultaneously at the pointed end. A higher monomer concentration is required to balance the association of actin monomers and the dissociation of filament subunits at the pointed end than at the barbed end.
Jean-Marc Neuhaus +3 more
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Biopolymers, 1991
AbstractThe total strain birefringence of F‐actin isolated from chicken gizzards was measured as a function of elongation in thin transparent films. Each film held at a certain elongation in a jig was allowed to swell in a penetrating but nondissolving liquid. Seven liquids with different refractive indices were employed.
Frederick A. Bettelheim +1 more
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AbstractThe total strain birefringence of F‐actin isolated from chicken gizzards was measured as a function of elongation in thin transparent films. Each film held at a certain elongation in a jig was allowed to swell in a penetrating but nondissolving liquid. Seven liquids with different refractive indices were employed.
Frederick A. Bettelheim +1 more
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Actin and Actin-Associated Proteins [PDF]
, 1995 A 240 KDa filamin equivalent protein from Dictyostelium discoideum, which crosslinks and bundles actin filaments at the cell cortex.
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Actin Kinase: A Protein Kinase That Phosphorylates Actin of Fragmin- Actin Complex1
The Journal of Biochemistry, 1992Actin of fragmin-actin complex is phosphorylated by an endogenous kinase from plasmodium of Physarum polycephalum. The phosphorylation abolishes the nucleation and capping activities of fragmin-actin complex. The kinase has been purified and termed actin kinase [Furuhashi, K. & Hatano, S. (1990) J. Cell Biol. 111, 1081-1087].
Kiyoshi Furuhashi, Sadashi Hatano
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Biochemical and mechanical regulation of actin dynamics
Nature reviews. Molecular cell biology, 2022P. Lappalainen +3 more
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