Results 1 to 10 of about 603 (118)
Role of Spectrin in Endocytosis
Cells, 2022 Cytoskeletal spectrin is found in (non)erythroid cells. Eukaryotic endocytosis takes place for internalizing cargos from extracellular milieu. The role of spectrin in endocytosis still remains poorly understood.
Donghai Li
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Computational and Structural Biotechnology Journal, 2021 Recent nanoscopy and super-resolution microscopy studies have substantiated the structural contribution of periodic actin-spectrin lattice to the axonal cytoskeleton of neuron.
Md Ishak Khan +2 more
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Competition between myosin II and βH-spectrin regulates cytoskeletal tension
eLife, 2023 Spectrins are membrane cytoskeletal proteins generally thought to function as heterotetramers comprising two α-spectrins and two β-spectrins. They influence cell shape and Hippo signaling, but the mechanism by which they influence Hippo signaling has ...
Consuelo Ibar +3 more
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Glycosylation of erythrocyte spectrin and its modification in visceral leishmaniasis. [PDF]
PLoS ONE, 2011 Using a lectin, Achatinin-H, having preferential specificity for glycoproteins with terminal 9-O-acetyl sialic acid derivatives linked in α2-6 linkages to subterminal N-acetylgalactosamine, eight distinct disease-associated 9-O-acetylated ...
Sajal Samanta +10 more
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Scientific Reports, 2021 The neuronal membrane-associated periodic spectrin skeleton (MPS) contributes to neuronal development, remodeling, and organization. Post-translational modifications impinge on spectrin, the major component of the MPS, but their role remains poorly ...
Arkadiusz Miazek +8 more
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The spectrin cytoskeleton is crucial for adherent and invasive bacterial pathogenesis. [PDF]
PLoS ONE, 2011 Various enteric bacterial pathogens target the host cell cytoskeletal machinery as a crucial event in their pathogenesis. Despite thorough studies detailing strategies microbes use to exploit these components of the host cell, the role of the spectrin ...
Tyson Ruetz +2 more
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β spectrin-dependent and domain specific mechanisms for Na+ channel clustering
eLife, 2020 Previously, we showed that a hierarchy of spectrin cytoskeletal proteins maintains nodal Na+ channels (Liu et al., 2020). Here, using mice lacking β1, β4, or β1/β4 spectrins, we show this hierarchy does not function at axon initial segments (AIS ...
Cheng-Hsin Liu +7 more
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Frontiers in Neurology, 2021 ßIV-spectrin is a protein of the spectrin family which is involved in the organization of the cytoskeleton structure and is found in high quantity in the axon initial segment and the nodes of Ranvier.
Aziza Miriam Belkheir +9 more
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318 Building A Better CAR: Improving CAR-T Trafficking in Cancer Therapy
Journal of Clinical and Translational Science, 2022 OBJECTIVES/GOALS: #NAME? METHODS/STUDY POPULATION: Cell culture & protein identification: human T cells were purified from healthy blood, then activated & cultured for 5d. CAR-T cells were collected from infusion bags of cancer patients undergoing CAR-T.
Yeonsun Hong +16 more
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αII-spectrin in T cells is involved in the regulation of cell-cell contact leading to immunological synapse formation? [PDF]
PLoS ONE, 2017 T-lymphocyte activation after antigen presentation to the T-Cell Receptor (TCR) is a critical step in the development of proper immune responses to infection and inflammation.
Justyna M Meissner +8 more
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