Results 21 to 30 of about 25,119 (232)
The Physiological Molecular Shape of Spectrin: A Compact Supercoil Resembling a Chinese Finger Trap. [PDF]
PLoS Computational Biology, 2015 The primary, secondary, and tertiary structures of spectrin are reasonably well defined, but the structural basis for the known dramatic molecular shape change, whereby the molecular length can increase three-fold, is not understood.
Jeffrey W Brown +5 more
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Erythroid and nonerythroid spectrins [PDF]
Blood, 1993 Abstract Recent developments have contributed important information to understanding the role of spectrins in the RBC membrane skeleton and nonerythroid cells. Many questions can now be framed, informed by structural knowledge of various spectrin subunit types and alternatively spliced variants, that previously could not have been ...
J C, Winkelmann, B G, Forget
openaire +3 more sources
Brazilian Journal of Medical and Biological Research, 2002 Hereditary spherocytosis (HS) is a common inherited anemia characterized by the presence of spherocytic red cells. Defects in several membrane protein genes have been involved in the pathogenesis of HS. ß-Spectrin-related HS seems to be common. We report
D.S. Bassères +3 more
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Memorias do Instituto Oswaldo Cruz, 2000 The invasion of the erythrocyte by Plasmodium falciparum depends on the ability of the merozoite to move through the membrane invagination. This ability is probably mediated by actin dependent motors.
Claudia Forero, Moisés Wasserman
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The actin binding domain of βI-spectrin regulates the morphological and functional dynamics of dendritic spines. [PDF]
PLoS ONE, 2011 Actin microfilaments regulate the size, shape and mobility of dendritic spines and are in turn regulated by actin binding proteins and small GTPases. The βI isoform of spectrin, a protein that links the actin cytoskeleton to membrane proteins, is present
Michael W Nestor +4 more
doaj +1 more source
EzrA: a spectrin-like scaffold in the bacterial cell division machinery
Microbial Cell, 2015 Much progress has been made in identifying the components of the divisome, the assembly of proteins that undertakes the vital process of cell division in bacteria.
Robert M Cleverley, Richard J Lewis
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β-spectrinBari: a truncated β-chain responsible for dominant hereditary spherocytosis
Haematologica, 2009 We describe a β-spectrin variant, named β-spectrin Bari, characterized by a truncated chain and associated with hereditary spherocytosis. The clinical phenotype consists of a moderately severe hemolytic anemia, splenomegaly, and spherocytes and ...
Silverio Perrotta +10 more
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Severe hereditary spherocytosis presenting with non-immune fetal hydrops
Indian Pediatrics Case Reports, 2023 Background: Hereditary spherocytosis (HS) is characterized by spherocytes on the peripheral smear and heterogeneous clinical presentation (mild, moderate, moderate/severe, and severe) depending upon the severity of hemolytic anemia, jaundice, and ...
Snehal Mallakmir +3 more
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Poultry Science, 2022 : The aim of the current study was to assess the influence of embryonic exposure to cadmium on basic and derived erythrocyte indices, the morphology and morphometric properties of erythrocytes, as well as erythrocyte spectrin distribution in newly ...
Bartosz Bojarski +11 more
doaj +1 more source
β Spectrin Functions Independently of α Spectrin to Polarize the Na,k Atpase in Epithelial Cells [PDF]
, 2000 Spectrin has been proposed to function as a sorting machine that concentrates interacting proteins such as the Na,K ATPase within specialized plasma membrane domains of polarized cells.
Ronald R. Dubreuil +9 more
core +1 more source