Results 261 to 270 of about 287,702 (305)

The Ultrastructure of the Apical Organ of the Goette's Larvae of the Polyclad Flatworm Stylochus pilidium Indicates Homology Between Polyclad Larvae

open access: yesCell Biology International, EarlyView.
ABSTRACT Polyclad flatworms exhibit both direct and indirect development, with various larval types observed, including Müller's larva, Kato's larva, Goette's larva and Curini‐Galletti's larva. The different larval types are distinguished by shape, number of eyes and number of lobes.
Davina Düngler   +5 more
wiley   +1 more source

A truncation mutant of adenomatous polyposis coli impairs apical cell extrusion through elevated epithelial tissue tension

open access: yesCytoskeleton, EarlyView.
Abstract Tissue tension encompasses the mechanical forces exerted on solid tissues within animal bodies, originating from various sources such as cellular contractility, interactions with neighboring cells and the extracellular matrix. Emerging evidence indicates that an imbalance in such forces can influence structural organization, homeostasis, and ...
Wan J. Gan   +7 more
wiley   +1 more source

Disruption of salt bridge interactions in the inter‐domain cleft of the tubulin‐like protein FtsZ of Escherichia coli makes cells sensitive to the cell division inhibitor PC190723

open access: yesCytoskeleton, EarlyView.
Abstract FtsZ forms a ring‐like assembly at the site of division in bacteria. It is the first protein involved in the formation of the divisome complex to split the cell into two halves, indicating its importance in bacterial cell division. FtsZ is an attractive target for developing new anti‐microbial drugs to overcome the challenges of antibiotic ...
Sakshi Mahesh Poddar   +3 more
wiley   +1 more source

The Heterotaxy Gene CCDC11 Is Important for Cytokinesis via RhoA Regulation

open access: yesCytoskeleton, EarlyView.
ABSTRACT Mutations in CCDC11 (cfap53) have been identified in multiple patients with heterotaxy (Htx), a disorder of left–right (LR) patterning of the internal organs. In Xenopus, depletion of Ccdc11 causes defects in LR patterning, recapitulating the patient phenotype. Upon Ccdc11 depletion, monociliated cells of the Left–Right Organizer (LRO) exhibit
Saurabh S. Kulkarni   +9 more
wiley   +1 more source

Unjamming Transition as a Paradigm for Biomechanical Control of Cancer Metastasis

open access: yesCytoskeleton, EarlyView.
ABSTRACT Tumor metastasis is a complex phenomenon that poses significant challenges to current cancer therapeutics. While the biochemical signaling involved in promoting motile phenotypes is well understood, the role of biomechanical interactions has recently begun to be incorporated into models of tumor cell migration.
Grace Cai   +2 more
wiley   +1 more source

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