Expanding science skills: teaching tissue culture, data analysis, and reporting through imaging the actin cytoskeleton. [PDF]
Harrison A, Evans G, Blanco G.
europepmc +1 more source
ABSTRACT Polyclad flatworms exhibit both direct and indirect development, with various larval types observed, including Müller's larva, Kato's larva, Goette's larva and Curini‐Galletti's larva. The different larval types are distinguished by shape, number of eyes and number of lobes.
Davina Düngler+5 more
wiley +1 more source
Actin Cytoskeleton Remodeling Accompanied by Redistribution of Adhesion Proteins Drives Migration of Cells in Different EMT States. [PDF]
Ilnitskaya AS+4 more
europepmc +1 more source
Abstract Tissue tension encompasses the mechanical forces exerted on solid tissues within animal bodies, originating from various sources such as cellular contractility, interactions with neighboring cells and the extracellular matrix. Emerging evidence indicates that an imbalance in such forces can influence structural organization, homeostasis, and ...
Wan J. Gan+7 more
wiley +1 more source
The amoeboid migration of monocytes in confining channels requires the local remodeling of the cortical actin cytoskeleton by cofilin-1. [PDF]
Ullo MF+3 more
europepmc +1 more source
Abstract FtsZ forms a ring‐like assembly at the site of division in bacteria. It is the first protein involved in the formation of the divisome complex to split the cell into two halves, indicating its importance in bacterial cell division. FtsZ is an attractive target for developing new anti‐microbial drugs to overcome the challenges of antibiotic ...
Sakshi Mahesh Poddar+3 more
wiley +1 more source
The Heterotaxy Gene CCDC11 Is Important for Cytokinesis via RhoA Regulation
ABSTRACT Mutations in CCDC11 (cfap53) have been identified in multiple patients with heterotaxy (Htx), a disorder of left–right (LR) patterning of the internal organs. In Xenopus, depletion of Ccdc11 causes defects in LR patterning, recapitulating the patient phenotype. Upon Ccdc11 depletion, monociliated cells of the Left–Right Organizer (LRO) exhibit
Saurabh S. Kulkarni+9 more
wiley +1 more source
PCP and Septins govern the polarized organization of the actin cytoskeleton during convergent extension. [PDF]
Devitt CC+4 more
europepmc +1 more source
Unjamming Transition as a Paradigm for Biomechanical Control of Cancer Metastasis
ABSTRACT Tumor metastasis is a complex phenomenon that poses significant challenges to current cancer therapeutics. While the biochemical signaling involved in promoting motile phenotypes is well understood, the role of biomechanical interactions has recently begun to be incorporated into models of tumor cell migration.
Grace Cai+2 more
wiley +1 more source
Actin cytoskeleton differently regulates cell surface organization of GPI-anchored proteins in polarized epithelial cells and fibroblasts. [PDF]
Lebreton S+5 more
europepmc +1 more source