Results 271 to 280 of about 287,702 (305)

Single‐Molecule Tracking and Super‐Resolution Microscopy Unveil Actin‐Driven Membrane Nanotopography Shaping Stable Integrin Adhesions in Developing Tissue

Cytoskeleton, EarlyView.
ABSTRACT Single molecule tracking and super‐resolution microscopy of integrin adhesion proteins and actin in developing Drosophila muscle attachment sites reveals that nanotopography triggered by Arp2/3‐dependent actin protrusions promotes stable adhesion formation.
Tianchi Chen, Cecilia H Fernández‐Espartero, Grégory Giannone   +2 more
wiley   +1 more source

Actin Filament Pointed Ends: Assays for Regulation of Assembly and Disassembly by Tropomodulin and Tropomyosin

Cytoskeleton, EarlyView.
ABSTRACT Actin filaments are dynamic polymers whose length depends on regulated monomer association and dissociation at their ends. Actin barbed‐end dynamics are relatively better understood, primarily due to the approximately tenfold faster subunit on/off rates at barbed versus pointed ends.
Sawako Yamashiro, Shashank Shekhar, Stefanie M. Novak, Sudipta Biswas, Carol C. Gregorio, Velia M. Fowler   +5 more
wiley   +1 more source

Phosphorylation at the Helm: Kinase‐Mediated Regulation of Primary Cilia Assembly and Disassembly

Cytoskeleton, EarlyView.
ABSTRACT The primary cilium serves as an antenna of most vertebrate cells and is important for conveying cues from several signaling pathways into appropriate cellular responses during development and homeostasis. Cilia assembly and disassembly processes are thought to be strictly controlled; however, the precise nature of molecular events underlying ...
Andrea Lacigová, Lukáš Čajánek
wiley   +1 more source

Thiazole-fused androstenone and ethisterone derivatives: potent β- and γ-actin cytoskeleton inhibitors to treat melanoma tumors. [PDF]

RSC Med Chem
Adhikary S, Roy S, Budhathoki S, Chowdhury S, Stillwell A, Basnakian AG, Tackett A, Avaritt N, Milad M, Alam MA.   +9 more
europepmc   +1 more source

<i>Lactiplantibacillus plantarum</i> (CECT7484 and CECT7485) and <i>Pedioccoccus acidilactici</i> (CECT7483) enhance actin cytoskeleton and CYP1A1 expression restoring epithelial permeability alterations induced by irritable bowel syndrome mediators. [PDF]

Gut Microbes
Barbaro MR, Bianco F, Cremon C, Marasco G, Bonomini F, Palombo M, Delprete C, Perez M, Espadaler-Mazo J, Stanghellini V, Guglielmetti S, Barbara G.   +11 more
europepmc   +1 more source

PCDH17 restricts dendritic spine morphogenesis by regulating ROCK2-dependent control of the actin cytoskeleton, modulating emotional behavior. [PDF]

Zool Res
Yu L, Zeng F, Fan M, Zhang K, Duan J, Tan Y, Liao P, Wen J, Wang C, Wang M, Yuan J, Pang X, Huang Y, Zhang Y, Li JD, Zhang Z, Hu Z.   +16 more
europepmc   +1 more source

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Visualising the actin cytoskeleton

Microscopy Research and Technique, 1999
The actin cytoskeleton is a dynamic filamentous network whose formation and remodeling underlies the fundamental processes of cell motility and shape determination. To serve these roles, different compartments of the actin cytoskeleton engage in forming specific coupling sites between neighbouring cells and with the underlying matrix, which themselves ...
Klemens Rottner, Kurt I. Anderson, J. Victor Small, Penelope Hahne   +3 more
openaire   +3 more sources

SIGNALING TO THE ACTIN CYTOSKELETON

Annual Review of Cell and Developmental Biology, 1998
▪ Abstract  The actin cytoskeleton is a highly dynamic network composed of actin polymers and a large variety of associated proteins. The main functions of the actin cytoskeleton are to mediate cell motility and cell shape changes during the cell cycle and in response to extracellular stimuli, to organize the cytoplasm, and to generate mechanical ...
Schmidt, A., Hall, M. N.
openaire   +3 more sources

The yeast actin cytoskeleton

Current Opinion in Cell Biology, 1994
Budding and fission yeast present significant advantages for studies of the actin cytoskeleton. The application of classical and molecular genetic techniques provides a facile route for the analysis of structure/function relationships, for the isolation of novel proteins involved in cytoskeletal function, and for deciphering the signals that regulate ...
Matthew D. Welch, David G. Drubin, Douglas A. Holtzman   +2 more
openaire   +2 more sources