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Role of actin cytoskeleton in podocytes

Pediatric Nephrology, 2020
The selectivity of the glomerular filter is established by physical, chemical, and signaling interplay among its three core constituents: glomerular endothelial cells, the glomerular basement membrane, and podocytes. Functional impairment or injury of any of these three components can lead to proteinuria.
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Cellular Ageing and the Actin Cytoskeleton

2011
For some time the view that the actin cytoskeleton acts primarily as a scaffold, to be assembled in response to a signaling cascade as an end point in the pathway, has prevailed. However, it is now clear that the dynamic nature of the cytoskeleton is linked to downstream signaling events that further modulate cellular activity, and which can determine ...
Campbell W. Gourlay   +3 more
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Membrane interactions with the actin cytoskeleton

Current Opinion in Cell Biology, 1994
Recent advances have been made in our understanding of the direct binding of actin to integral membrane proteins. New information has been obtained about indirect actin-membrane associations through spectrin superfamily members and through proteins at the cytoplasmic surfaces of focal contacts and adherens junctions.
Elizabeth J. Luna, Anne L. Hitt
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Actin and microtubule cytoskeleton interactions

Current Opinion in Plant Biology, 2009
Plant cytoskeleton consists of two major networks of protein polymers, actin microfilaments (AFs) and microtubules (MTs). These networks perform numerous functions that are essential for cell division and for maintaining the integrity of cytoplasm required for intracellular transport and cell shape. Besides the more or less indirect cooperation between
Jan Petrášek, Kateřina Schwarzerová
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The Actin Cytoskeleton in T Cell Activation

Annual Review of Immunology, 2008
T cell cytoarchitecture differs dramatically depending on whether the cell is circulating within the bloodstream, migrating through tissues, or interacting with antigen-presenting cells. The transition between these states requires important signaling-dependent changes in actin cytoskeletal dynamics.
Janis K. Burkhardt   +2 more
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Actin cytoskeleton and cell signaling

Critical Care Medicine, 2000
The role of the actin cytoskeleton in the function of eukaryotic cells is ubiquitous. Regulation of actin polymerization allows cells to control their shape, to move, divide, secrete, and phagocytose. Actin filaments provide strength, connections to other cells and the extracellular matrix, paths for intracellular transport and a scaffold for ...
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Connecting membranes to the actin cytoskeleton

Current Opinion in Plant Biology, 2017
In plants, the actin cytoskeleton plays a major role in organelle movement, cargo transport, maintaining cell polarity and controlling the morphogenesis of endomembrane systems. All of these events require a direct connection between membrane structures and the cytoskeleton.
Pengwei Wang   +2 more
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[The actin cytoskeleton goes retroviral].

Medecine sciences : M/S, 2017
International ...
Teruel, Élodie   +3 more
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Actin Cytoskeleton: Through the bottleneck

Current Biology, 1994
Like serendipity-alpha and nullo, the newly characterized gene bottleneck is involved in organizing the actin cytoskeleton of the Drosophila embryo to achieve the transition from a syncytium to a cellular blastoderm.
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Rho GTPases and the Actin Cytoskeleton

Science, 1998
The actin cytoskeleton mediates a variety of essential biological functions in all eukaryotic cells. In addition to providing a structural framework around which cell shape and polarity are defined, its dynamic properties provide the driving force for cells to move and to divide. Understanding the biochemical mechanisms that control the organization of
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