Results 291 to 300 of about 519,825 (333)

Role of actin cytoskeleton in podocytes

Pediatric Nephrology, 2020
The selectivity of the glomerular filter is established by physical, chemical, and signaling interplay among its three core constituents: glomerular endothelial cells, the glomerular basement membrane, and podocytes. Functional impairment or injury of any of these three components can lead to proteinuria.
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The Actin Cytoskeleton in T Cell Activation

Annual Review of Immunology, 2008
T cell cytoarchitecture differs dramatically depending on whether the cell is circulating within the bloodstream, migrating through tissues, or interacting with antigen-presenting cells. The transition between these states requires important signaling-dependent changes in actin cytoskeletal dynamics.
Janis K, Burkhardt, Esteban, Carrizosa, Meredith H, Shaffer   +2 more
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Prokaryotic origin of the actin cytoskeleton

Nature, 2001
It was thought until recently that bacteria lack the actin or tubulin filament networks that organize eukaryotic cytoplasm. However, we show here that the bacterial MreB protein assembles into filaments with a subunit repeat similar to that of F-actin-the physiological polymer of eukaryotic actin.
F, van den Ent, L A, Amos, J, Löwe
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Cellular Ageing and the Actin Cytoskeleton

2011
For some time the view that the actin cytoskeleton acts primarily as a scaffold, to be assembled in response to a signaling cascade as an end point in the pathway, has prevailed. However, it is now clear that the dynamic nature of the cytoskeleton is linked to downstream signaling events that further modulate cellular activity, and which can determine ...
David, Amberg, Jane E, Leadsham, Vasillios, Kotiadis, Campbell W, Gourlay   +3 more
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Membrane interactions with the actin cytoskeleton

Current Opinion in Cell Biology, 1994
Recent advances have been made in our understanding of the direct binding of actin to integral membrane proteins. New information has been obtained about indirect actin-membrane associations through spectrin superfamily members and through proteins at the cytoplasmic surfaces of focal contacts and adherens junctions.
A L, Hitt, E J, Luna
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Apoptosis and the yeast actin cytoskeleton

Cell Death & Differentiation, 2009
Actin represents one of the most abundant and extensively studied proteins found in eukaryotic cells. It has been identified as a major target for destruction during the process of apoptosis. Recent research has also highlighted a role for cytoskeletal components in the initiation and inhibition of apoptotic processes.
J E, Leadsham, V N, Kotiadis, D J, Tarrant, C W, Gourlay   +3 more
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Functional design in the actin cytoskeleton

Current Opinion in Cell Biology, 1999
Changes in cell shape, anchorage and motility are all associated with the dynamic reorganisation of the architectural arrays of actin filaments that make up the actin cytoskeleton. The relative expression of these functionally different actin filament arrays is intimately linked to the pattern of contacts that a cell develops with its extracellular ...
J V, Small, K, Rottner, I, Kaverina
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Actin Cytoskeleton: Through the bottleneck

Current Biology, 1994
Like serendipity-alpha and nullo, the newly characterized gene bottleneck is involved in organizing the actin cytoskeleton of the Drosophila embryo to achieve the transition from a syncytium to a cellular blastoderm.
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Medical aspects of the actin cytoskeleton

Current Opinion in Cell Biology, 1995
The actin cytoskeleton is affected in many disease states. The mechanisms by which altered structure or expression of actin or of actin-binding proteins cause specific defects are beginning to emerge. Notable recent findings concern the roles in tumor suppression of proteins that link actin to the cell membrane, the specific functions of actin isoforms
Janmey, P. A., Chaponnier, Christine
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Actin and microtubule cytoskeleton interactions

Current Opinion in Plant Biology, 2009
Plant cytoskeleton consists of two major networks of protein polymers, actin microfilaments (AFs) and microtubules (MTs). These networks perform numerous functions that are essential for cell division and for maintaining the integrity of cytoplasm required for intracellular transport and cell shape. Besides the more or less indirect cooperation between
Jan, Petrásek, Katerina, Schwarzerová
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