Results 101 to 110 of about 14,232,320 (254)

TRIM32 controls timely cell cycle exit in muscular differentiation through downregulation of c‐Myc mRNA

open access: yesThe FEBS Journal, EarlyView.
Trim32 regulates the transition from proliferation to differentiation in C2C12 cells after myogenic induction. We found that, at the onset of differentiation, Trim32 destabilizes c‐Myc mRNA, promotes cell cycle exit, and enables normal myotube formation.
Lu Xiong   +6 more
wiley   +1 more source

Antimicrobial Profile of Actinomycin D Analogs Secreted by Egyptian Desert Streptomyces sp. DH7. [PDF]

open access: yesAntibiotics (Basel), 2021
Amin DH   +4 more
europepmc   +1 more source

Dual IRE1 targets: Determinants of the cell fate?

open access: yesThe FEBS Journal, EarlyView.
IRE1 is an ER stress sensor that restores protein homeostasis through two signaling activities: XBP1s, which upregulates its target gene expression or RIDD which downregulates its target transcripts. We recently identified Dual IRE1 Targets (DIT) which are modulated by both XBP1s and RIDD activities.
Eva Billat   +3 more
wiley   +1 more source

Late recurrence in children with Wilms' tumor

open access: yesThe Turkish Journal of Pediatrics, 2007
We aimed in this study to evaluate the clinical and radiological features of the late recurrence of Wilms' tumor in children. Among 553 children diagnosed with Wilms' tumor between 1972 and 2004, four cases were determined to be late recurrences ...
Münevver Büyükpamukçu   +7 more
doaj  

Hypoxia‐preconditioned adipose‐derived mesenchymal stem cells‐derived exosomes transferring H19 obstruct neutrophil extracellular traps formation via HOXA5‐mediated inactivation of TLR4/NF‐κB/NLRP3 inflammatory signaling

open access: yesJournal of Diabetes Investigation, EarlyView.
In this study, we uncovered that Hypo‐Exo transferring H19 promoted diabetic wound healing by repressing NETs formation via the miR‐130a/b‐3p/HOXA5 pathway to inactivate the TLR4/NF‐κB/NLRP3 inflammatory signaling. ABSTRACT Background Hypoxia‐stimulated adipose‐derived mesenchymal stem cells (ADSCs)‐derived exosomes (Hypo‐Exo) have a positive impact on
Li Qian   +3 more
wiley   +1 more source

Toxicity and pharmacokinetics of actinomycin-D and vincristine in children and adolescents: Children's Oncology Group Study ADVL06B1. [PDF]

open access: yesCancer Chemother Pharmacol, 2021
Skolnik J   +8 more
europepmc   +1 more source

Intra‐apheresis CD34+ cell count: A dynamic approach to predicting peripheral blood stem cell collection yield

open access: yesTransfusion, EarlyView.
Abstract Background Accurate prediction of peripheral blood stem cell (PBSC) yield is essential for optimizing hematopoietic stem cell collections. Traditional CD34+ prediction formulas often overlook the ongoing recruitment of CD34+ cells during the collection procedure.
Abdullah Alswied   +8 more
wiley   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

open access: yesPediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait   +23 more
wiley   +1 more source

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