Synergistic activation of p53 by actinomycin D and nutlin-3a is associated with the upregulation of crucial regulators and effectors of innate immunity. [PDF]
Cell Signal, 2020 Krześniak M +5 more
europepmc +1 more source
The effect of fasting, diet, and actinomycin D on insulin secretion in the rat.
Journal of Clinical Investigation, 1970 N. Grey, S. Goldring, D. Kipnis
semanticscholar +1 more source
GPSM2 Promotes Pancreatic Cancer Progression Through METTL3‐Mediated m6A Modification of YAP1 mRNA
Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.ABSTRACT Pancreatic cancer poses a major therapeutic challenge due to its insidious onset and difficulty in early diagnosis. G‐protein signalling modulator 2 (GPSM2), a member of the G‐protein signalling regulator family, is highly expressed in various tumour tissues; however, its role in pancreatic cancer remains largely undefined.
Jiajun Xiu +9 more
wiley +1 more source
Messenger RNA turnover and protein synthesis in B. subtilis inhibited by actinomycin D.
Proceedings of the National Academy of Sciences of the United States of America, 1962 C. Levinthal, A. Keynan, A. Higa
semanticscholar +1 more source
Potential Relationship Between YTHDF3 and CFTR in Myocardial Ischemia–Reperfusion Injury
Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.ABSTRACT Myocardial ischemia–reperfusion injury (MIRI) is a common pathophysiological process in reperfusion therapy following myocardial infarction. It exacerbates myocardial damage and negatively impacts patient prognosis. This study aims to explore potential regulatory targets and related mechanisms in MIRI.
Baoxin Tang +4 more
wiley +1 more source
METTL3/YTHDF1‐Driven SURF6 Promotes Prostate Cancer Stemness via CDK4
Journal of Cellular and Molecular Medicine, Volume 30, Issue 12, June 2026.ABSTRACT Prostate cancer (PCa) remains a major health challenge globally, necessitating the identification of novel therapeutic targets to improve patient outcomes. This study investigates the role of the SURF6 gene in PCa, focusing on its expression patterns, molecular mechanisms, and biological behaviours in vitro and in vivo.
Yue Cheng +3 more
wiley +1 more source
Veterinary and Comparative Oncology, Volume 24, Issue 2, Page 382-392, June 2026.ABSTRACT Primary mediastinal lymphoma is rare in dogs and literature exploring this disease is limited. Therefore, the aim of this study was to describe presentation, treatment and outcome in a large cohort of dogs with mediastinal lymphoma and explore prognostic factors including chemotherapy protocol. This retrospective multi‐institute study included
Diogo Machado +11 more
wiley +1 more source
Increasing the human chorionic gonadotrophin cut-off to ≤1000 IU/l for starting actinomycin D in post-molar gestational trophoblastic neoplasia developing resistance to methotrexate spares more women multi-agent chemotherapy. [PDF]
ESMO Open, 2021 Cortés-Charry R +11 more
europepmc +1 more source
Successful treatment using Actinomycin D in a case of methotrexate-resistant ectopic pregnancy: A case report. [PDF]
Med J Islam Repub Iran, 2019 Aminimoghaddam S, Omranipoor A.
europepmc +1 more source