Results 31 to 40 of about 14,232,320 (254)
Bioactive secondary metabolites from two sponge-derived actinomycetes
Shenzhen Daxue xuebao. Ligong ban, 2022 Actinomycetes residing in marine habitat are an excellent treasure house of structurally novel and bioactive natural products with potent medicinal values.
GUO Zhikai +5 more
doaj +1 more source
Hepatology, EarlyView., 2022 A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan +19 more
wiley +1 more source
Heliyon, 2023 Invasive fungal infections are on the rise, leading to a continuous demand for antifungal antibiotics. Rare actinomycetes have been shown to contain a variety of interesting compounds worth exploring.
Wenbin Liu +7 more
doaj +1 more source
Antifungal effects of actinomycin D on Verticillium dahliae via a membrane-splitting mechanism
Natural Product Research, 2019 Antifungal bioassays led to the isolation of actinomycins D and A1 from Streptomyces luteus TRM45540 collected from Norpo in Xinjiang, and these compounds were identified by nuclear magnetic resonance spectroscopy.
H. Zeng, Pei-Xian Feng, C. Wan
semanticscholar +1 more source
Effect of low doses of actinomycin D on neuroblastoma cell lines
Molecular Cancer, 2016 Neuroblastoma is a malignant embryonal tumor occurring in young children, consisting of undifferentiated neuroectodermal cells derived from the neural crest.
Constanza Cortés +8 more
semanticscholar +1 more source
Diagnosis, classification and treatment of gestational trophoblastic neoplasia [PDF]
Revista Brasileira de Ginecologia e Obstetrícia, 2015 Gestational trophoblastic neoplasia (GTN) is the term to describe a set of malignant placental diseases, including invasive mole, choriocarcinoma, placental site trophoblastic tumor and epithelioid trophoblastic tumor.
Andressa Biscaro +2 more
doaj +1 more source
Microorganisms, 2020 Ralstonia solanacearum is an important soil-borne bacterial plant pathogen. In this study, an actinomycete strain named NEAU-HV9 that showed strong antibacterial activity against Ralstonia solanacearum was isolated from soil using an in vitro screening ...
Ling Ling +10 more
doaj +1 more source
THE FACTORS THAT AFFECT STAPHYLOCCUS AUREUS CELL WALL SYNTHESIS AND RESISTANCE TO ACTINOMYCIN D
Антибиотики и Химиотерапия, 2020 The cells of the strain S.aureus R80 strain, resistant to actinomycin D, possess a cell wall, thickened as a result of additional synthesis of peptidoglycan.
V. G. Bulgakova +2 more
doaj
Action of actinomycin D on auxin-induced growth of Avena coeleoptile section
Acta Societatis Botanicorum Poloniae, 2015 Double-stranded DNA and in a lesser degree ATP reduce the inhibitory action of actinomycin D on auxin-induced elongation growth. The reduction of inhibition by DNA is significant in the initial phase of elongation up to the 4th hour of growth. The effect
J. Buczek
doaj +1 more source
Clinical Pharmacokinetics, 2014 Background and ObjectiveDespite its important role in cancer treatment, there is currently very limited available information concerning the clinical pharmacology of actinomycin D (Act D). The study was designed to characterise Act D pharmacokinetics and
C. R. Hill +5 more
semanticscholar +1 more source