Results 111 to 120 of about 77,276 (354)
Leiomyosarcoma of the Inferior Venacava: A Case Report
Journal of Nepal Medical Association, 2019 Leiomyosarcoma of inferior venacava is a rare tumor. Female are most commonly affected and middle segment of inferior vena cava is the commonest site. The diagnosis can sometimes be challenging as patients present with non-specific symptoms. We present a
Diksha Karki +7 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Finite-Width Bundle is Most Stable in a Solution with Salt
, 2010 We applied the mean-field approach to a columnar bundle assembled by the parallel arrangement of stiff polyelectrolyte rods in a salt bath. The electrostatic potential can be divided into two regions: inside the bundle for condensed counter-ions, and ...
Kenichi Yoshikawa +2 more
core +1 more source
Mechanisms of actin disassembly and turnover [PDF]
, 2023 Bruce L. Goode +2 more
openalex +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Atomic view into Plasmodium actin polymerization, ATP hydrolysis, and fragmentation.
PLoS Biology, 2019 Plasmodium actins form very short filaments and have a noncanonical link between ATP hydrolysis and polymerization. Long filaments are detrimental to the parasites, but the structural factors constraining Plasmodium microfilament lengths have remained ...
Esa-Pekka Kumpula +4 more
doaj +1 more source
Multiple essential functions of Plasmodium falciparum actin-1 during malaria blood-stage development
BMC Biology, 2017 Background The phylum Apicomplexa includes intracellular parasites causing immense global disease burden, the deadliest of them being the human malaria parasite Plasmodium falciparum, which invades and replicates within erythrocytes.
Sujaan Das +4 more
doaj +1 more source
KRAP tethers IP3 receptors to actin and licenses them to evoke cytosolic Ca2+ signals [PDF]
, 2021 Nagendra Babu Thillaiappan +3 more
openalex +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source