Results 281 to 290 of about 75,213 (335)

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

Advanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu, Fenghui Wang, Joshua Stein, Siqiao Wang, Pengfei Jiang, Letao Yang, Liming Cheng, Ki‐Bum Lee   +7 more
wiley   +1 more source

The complete absence of cytoplasmic γ-actin results in no discernible phenotype in mice or primary fibroblasts. [PDF]

FEBS J
Sundby LJ, Hawbaker KM, Powers J, Southern WM, Johnson EE, Patrinostro X, Perrin BJ, Ervasti JM.   +7 more
europepmc   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Senescence-associated secretory phenotype regulation by dual-drug delivery biomimetic nanoplatform for enhanced tumor chemotherapy. [PDF]

Mol Ther Oncol
Prakash A, Gates T, Lou E.
europepmc   +1 more source

Engineering Highly Cellularized Living Materials via Mechanical Agitation

Advanced Functional Materials, EarlyView.
A mechanical agitation strategy is developed to engineer highly cellularized living materials, achieving cell densities of up to 1 billion cells per milliliter. By precisely tuning properties such as stiffness and toughness in blood clots, the approach is validated in both in vitro and in vivo studies.
Aram Bahmani, Shiyu Liu, Evan Johnston, Weiyi Wan, Xiaoyi Lan, Tianqin Ning, Alexander Nottegar, Ran Huo, Shuaibing Jiang, Jianyu Li   +9 more
wiley   +1 more source

Ultrastructural and Immunohistochemical Study of a Gastric Bizarre Leiomyoma: Bizarre Nuclei and Prominent Cytoplasmic Processes Extending Into and Displacing the Stroma. [PDF]

Pathol Int
Furihata K, Iwashita W, Kurabayashi A, Koji K, Furihata M.   +4 more
europepmc   +1 more source

Development of Substrate‐Independent Antifouling and Bactericidal Surfaces Using Visible Light Cross‐Linked Hydrogel Coatings for Biomedical Applications

Advanced Healthcare Materials, EarlyView.
A new antifouling, antithrombogenic, and bactericidal hydrogel coating method is developed for implantable medical devices. The hydrogel coating can be easily formed by visible‐light crosslinking and is universally applicable to all substrates, ranging from polymers to metals.
Soonjong Roh, Se Youn Jang, Youngmee Jung, Kangwon Lee, Jin Yoo   +4 more
wiley   +1 more source

Actin network evolution as a key driver of eukaryotic diversification.

J Cell Sci
Velle KB, Swafford AJM, Garner E, Fritz-Laylin LK.   +3 more
europepmc   +1 more source

β-actin function in platelets and red blood cells can be performed by γ-actin and is therefore independent of actin isoform protein sequence. [PDF]

Mol Biol Cell
Chakravarty D, Vedula P, Coffin M, Chen L, Sterling S, Peshkova AD, Suzuki A, Zhao L, Patra K, Assenmacher CA, Radaelli E, Levine M, Litvinov RI, Abrams CS, Fowler VM, Kashina A.   +15 more
europepmc   +1 more source

Regulation of Neurotransmitter Release by a Complex of Actin with Relaxing Protein Isolated from Rat Brain Synaptosomes

, 1974
Saul Puszkin, Shaul Kochwa
openalex   +1 more source