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It is well known that cardiac electromechanical delay (EMD) can cause dyssynchronous heart failure (DHF), a prominent cardiovascular disease (CVD). This work computationally assesses the conductance variation of every ion channel on the cardiac cell to ...
Ali Ikhsanul Qauli +2 more
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A Simple and Low-Cost, but Naturalistic Method for Introducing Students to Action Potentials
Current trends in science education recommend the complementary use of virtual and hands-on methods of teaching. In neurobiology, for instance, there is a plethora of virtual laboratories and simulators that can be readily combined with traditional ...
Orlando Jorquera, Edgar Harry Vogel
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Resilience of compound action potential peaks to high‐frequency firing in the mouse optic nerve
Action potential conduction in axons triggers trans‐membrane ion movements, where Na+ enters and K+ leaves axons, leading to disruptions in resting trans‐membrane ion gradients that must be restored for optimal axon conduction, an energy dependent ...
Amy J. Hopper +2 more
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Differences in Intersubject Early Readiness Potentials Between Voluntary and Instructed Actions
Readiness potential (RP) is a slow negative electroencephalogram (EEG) potential prior to voluntary action and was first described by Kornhuber and Deecke (1965).
Lipeng Zhang +11 more
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IntroductionAtrial fibrillation (AF) is the most common sustained cardiac arrhythmia and is associated with increased mortality and morbidity. The Exchange Protein directly Activated by cAMP (EPAC), has been implicated in pro-arrhythmic signaling ...
Bastien Guillot +24 more
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Synaptic input and temperature influence sensory coding in a mechanoreceptor
Many neurons possess more than one spike initiation zone (SIZ), which adds to their computational power and functional flexibility. Integrating inputs from different origins is especially relevant for sensory neurons that rely on relative spike timing ...
Jens-Steffen Scherer +5 more
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Biophysically detailed mathematical models of cardiac electrophysiology provide an alternative to experimental approaches for investigating possible ionic mechanisms underlying the genesis of electrical action potentials and their propagation through the
Henggui Zhang +8 more
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Activin A Reduces GIRK Current to Excite Dentate Gyrus Granule Cells
Activin A, a member of the TGF-β family, is recognized as a multifunctional protein in the adult brain with a particular impact on neuronal circuits associated with cognitive and affective functions.
Fang Zheng +3 more
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ALTERNATIVE TO Q WAVE DIAGNOSIS USING CARDIAC ACTION POTENTIAL PROPAGATION TIME MEASUREMENT
The diagnosis of myocardial infarction is done by ECG through the observation of Q waves in one or more leads. The paper describes the relationship between Q waves and the propagation time of the Cardiac Action potential and a technique by which this ...
S. Ananthi, V. Vignesh, K. Padmanabhan
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Gap junctions provide pathways for intercellular communication between adjacent cells, allowing exchange of ions and small molecules. Based on the constituent protein subunits, gap junctions are classified into different subtypes varying in their ...
Shailesh Appukuttan +2 more
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