Results 1 to 10 of about 1,814,108 (154)

Sensitivity Analysis of Ion Channel Conductance on Myocardial Electromechanical Delay: Computational Study

open access: yesFrontiers in Physiology, 2021
It is well known that cardiac electromechanical delay (EMD) can cause dyssynchronous heart failure (DHF), a prominent cardiovascular disease (CVD). This work computationally assesses the conductance variation of every ion channel on the cardiac cell to ...
Ali Ikhsanul Qauli   +2 more
doaj   +1 more source

A Simple and Low-Cost, but Naturalistic Method for Introducing Students to Action Potentials

open access: yesBrazilian Archives of Biology and Technology, 2021
Current trends in science education recommend the complementary use of virtual and hands-on methods of teaching. In neurobiology, for instance, there is a plethora of virtual laboratories and simulators that can be readily combined with traditional ...
Orlando Jorquera, Edgar Harry Vogel
doaj   +1 more source

Resilience of compound action potential peaks to high‐frequency firing in the mouse optic nerve

open access: yesPhysiological Reports, 2023
Action potential conduction in axons triggers trans‐membrane ion movements, where Na+ enters and K+ leaves axons, leading to disruptions in resting trans‐membrane ion gradients that must be restored for optimal axon conduction, an energy dependent ...
Amy J. Hopper   +2 more
doaj   +1 more source

Differences in Intersubject Early Readiness Potentials Between Voluntary and Instructed Actions

open access: yesFrontiers in Psychology, 2020
Readiness potential (RP) is a slow negative electroencephalogram (EEG) potential prior to voluntary action and was first described by Kornhuber and Deecke (1965).
Lipeng Zhang   +11 more
doaj   +1 more source

Inhibition of EPAC1 signaling pathway alters atrial electrophysiology and prevents atrial fibrillation

open access: yesFrontiers in Physiology, 2023
IntroductionAtrial fibrillation (AF) is the most common sustained cardiac arrhythmia and is associated with increased mortality and morbidity. The Exchange Protein directly Activated by cAMP (EPAC), has been implicated in pro-arrhythmic signaling ...
Bastien Guillot   +24 more
doaj   +1 more source

Synaptic input and temperature influence sensory coding in a mechanoreceptor

open access: yesFrontiers in Cellular Neuroscience, 2023
Many neurons possess more than one spike initiation zone (SIZ), which adds to their computational power and functional flexibility. Integrating inputs from different origins is especially relevant for sensory neurons that rely on relative spike timing ...
Jens-Steffen Scherer   +5 more
doaj   +1 more source

A Mathematical Model of the Mouse Atrial Myocyte With Inter-Atrial Electrophysiological Heterogeneity

open access: yesFrontiers in Physiology, 2020
Biophysically detailed mathematical models of cardiac electrophysiology provide an alternative to experimental approaches for investigating possible ionic mechanisms underlying the genesis of electrical action potentials and their propagation through the
Henggui Zhang   +8 more
doaj   +1 more source

Activin A Reduces GIRK Current to Excite Dentate Gyrus Granule Cells

open access: yesFrontiers in Cellular Neuroscience, 2022
Activin A, a member of the TGF-β family, is recognized as a multifunctional protein in the adult brain with a particular impact on neuronal circuits associated with cognitive and affective functions.
Fang Zheng   +3 more
doaj   +1 more source

ALTERNATIVE TO Q WAVE DIAGNOSIS USING CARDIAC ACTION POTENTIAL PROPAGATION TIME MEASUREMENT

open access: yesРоссийский кардиологический журнал, 2016
The diagnosis of myocardial infarction is done by ECG through the observation of Q waves in one or more leads. The paper describes the relationship between Q waves and the propagation time of the Cardiac Action potential and a technique by which this ...
S. Ananthi, V. Vignesh, K. Padmanabhan
doaj   +1 more source

Effect of Variations in Gap Junctional Coupling on the Frequency of Oscillatory Action Potentials in a Smooth Muscle Syncytium

open access: yesFrontiers in Physiology, 2021
Gap junctions provide pathways for intercellular communication between adjacent cells, allowing exchange of ions and small molecules. Based on the constituent protein subunits, gap junctions are classified into different subtypes varying in their ...
Shailesh Appukuttan   +2 more
doaj   +1 more source

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