Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Symmetry-based derivation of neuronal membrane dynamics: a Lie group approach to action potential generation. [PDF]
Melendy RF, Blue DH.
europepmc +1 more source
Project at Bocatoma The Eastern slopes of the Andes in North Peru are among the least developed parts of the country with the majority of people living in remote villages with little or no access to grid electricity.
Practical Action Peru
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Efficacy of sodium channel blockers in treating myotonia is independent of action potential sodium current block. [PDF]
Walker P +9 more
europepmc +1 more source
The Eastern slopes of the Andes in North Peru are among the least developed parts of the country with the majority of people living in remote villages with little or no access to grid electricity.
Practical Action Peru
core
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Robust activity-dependent mitochondrial calcium dynamics at the AIS is dispensable for action potential generation. [PDF]
Kole K, Kole MHP.
europepmc +2 more sources
Stochasticity in action potential backpropagation: consequences for neuronal computation. [PDF]
Antic SD, Milicevic KD, Lytton WW.
europepmc +1 more source
Action for Soviet Jewry events (110 digital images)
Action for Soviet Jewry events: Avital Sharansky with Governor Dukakis; Action for Soviet Jewry events, including Soviet Jewry Culture Cruise and photographs with R. Gordon, R. Drinan, Lynn Singer, Refuseniks Kornfeld, Branover. and Bayard Rustin.Digital
Action for Soviet Jewry
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