Results 241 to 250 of about 13,026,798 (304)

Spatial characterization of backpropagating action potential-evoked Ca²⁺ signals in human cortical layer 2/3 pyramidal neurons. [PDF]

Front Synaptic Neurosci
Szöts I, Tóth M, Ludányi C, Barzó P, Csajbók ÉA, Tamás G, Molnár G.   +6 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Subarachnoid hemorrhage mediates human neocortical network, membrane potential, and action potential bursting via glutamate receptors. [PDF]

Commun Biol
Huang DF, Chou MY, Lee YH, Chen YT, Sun CK, Wang KC, Huang HS.   +6 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Adaptations of the axon initial segment in fast-spiking interneurons of the human neocortex support low action potential thresholds. [PDF]

PLoS Biol
Bakos E, Tiszlavicz Á, Szegedi V, Douida A, Furdan S, Welter DK, Landry JM, Bende B, Hutoczki G, Barzo P, Tamas G, Benes V, Szucs A, Lamsa K.   +13 more
europepmc   +1 more source

Impact of Evoked Compound Action Potential (ECAP)-Controlled Closed-Loop Spinal Cord Stimulation in Refractory Lumbar Radiculopathy: A Case Report. [PDF]

Cureus
Soin A, Kassis S, Witte RJ, Sloop B, Brittain C.   +4 more
europepmc   +1 more source

The Role of Exosomes as a Key Factor of Cytostatic Resistance in Cancer: Mechanisms of Action, Potential Biomarkers, and Possible Exosome-Based Therapies. [PDF]

Oncol Res
Kałużna S, Świerczewska M, Ciesiółka S, Partyka M, Nowicki M, Wojtowicz K.   +5 more
europepmc   +1 more source

Coumarins in Anticancer Therapy: Mechanisms of Action, Potential Applications and Research Perspectives. [PDF]

Pharmaceutics
Kubrak TP, Makuch-Kocka A, Aebisher D.
europepmc   +1 more source

Focus on Sudan: a country of huge potential

, 2011
Practical Action
core  

A silent Kv channel subunit shapes PV neuron action potential waveform and short-term synaptic plasticity during high-frequency firing. [PDF]

Proc Natl Acad Sci U S A
Ganesh S, Canty TM, Sabatini BL.
europepmc   +1 more source