Results 71 to 80 of about 40,111 (286)

Allergenicity, Genotoxicity and Subchronic Toxicity Assessment of IgG Binding Protein LT Produced From Aspergillus oryzae

Journal of Applied Toxicology, EarlyView.
ABSTRACT Gastrointestinal health is one of the fastest growing areas in the food and beverage industry, as its importance to overall health and well‐being is becoming increasingly recognized. Immunoglobulins play a key role in protecting the gastrointestinal tract, and nonbovine sources of immunoglobulins (including camel milk, which has a long history
Kirt R. Phipps, Sachin Patel, Kevin Scaife, Toby Holmes, Alica Šoltésová, Sandra Wingaard Thrane, Louise Kristine Vigsnæs, Nigel Baldwin, Christel Jørgensen   +8 more
wiley   +1 more source

Autochthonous Babesia canis infections in 49 dogs in Germany

Journal of Veterinary Internal Medicine, Volume 37, Issue 1, Page 140-149, January/February 2023., 2023
Abstract Background Vector‐borne diseases are of increasing importance in Germany. Since 2015, autochthonous cases have been increasingly documented in Berlin/Brandenburg. Objectives Describe autochthonous Babesia canis infection in the Berlin/Brandenburg region. Animals Forty‐nine dogs with autochthonous B. canis infection.
Christiane Weingart, Christina S. Helm, Elisabeth Müller, Ingo Schäfer, Marianne Skrodzki, Georg von Samson‐Himmelstjerna, Jürgen Krücken, Barbara Kohn   +7 more
wiley   +1 more source

Medical conditions associated with Prolonged Activated Partial Thromboplastin time in Swat

Gomal Journal of Medical Sciences, 2010
Background: APPT is a commonly requested laboratory test in various bleeding conditions and as a screening test preoperatively. It is also used to monitor heparin therapy.
Mukamil Shah, Imran ud Din Khattak, Sania Tanweer Khattak, Ahad Abdul, Muhammad Amin Jan Mahsud   +4 more
doaj  

Clot waveform analysis of prolonged activated partial thromboplastin time in various disorders

Indian Journal of Pathology and Microbiology
Introduction: The prolongation in APTT reflects various disorders affecting the blood coagulation system. Automated coagulation analyzers such as ACL TOP, help in evaluating the clotting cascade by displaying clot reaction curves or waveforms. The fibrin
Apeksha Kadu, Ami M. Shah, Hansa Goswami
doaj   +1 more source

Efanesoctocog Alfa Population Pharmacokinetics and Repeated Time‐To‐Event Analysis of Bleeds in Adults, Adolescents, and Children with Severe Hemophilia A

The Journal of Clinical Pharmacology, EarlyView.
Abstract Efanesoctocog alfa is a first‐in‐class high‐sustained factor VIII (HSF) replacement therapy for treatment of hemophilia A. This article presents population pharmacokinetics (PopPK) of efanesoctocog alfa and repeated time‐to‐event (RTTE) analysis of bleeding episodes in adults/adolescents (≥12 years of age) and children (<12 years).
Nancy Wong, Pratik Bhagunde, Joakim Nyberg, Suresh Katragadda, Marek Demissie, Annemieke Willemze, Craig Benson, Sreeraj Macha   +7 more
wiley   +1 more source

Trends in the Outcomes of Advanced Hepatobiliary‐Pancreatic Surgery: The Impact of a Nationwide Clinical Database and Surgeon Certification System

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background The Japanese Society of Hepatobiliary and Pancreatic Surgery has established a certification system for experienced surgeons. Evaluating its efficacy requires accounting for patient risk variations. The National Clinical Database (NCD) facilitates this using risk‐adjusted outcome measures to validate and compare surgical performance.
Takayuki Anazawa, Hiroyuki Yamamoto, Etsuro Hatano, Mitsukazu Gotoh, Masafumi Nakamura, Masayuki Ohtsuka, Itaru Endo   +6 more
wiley   +1 more source

Thromboelastography Maximum Amplitude Is a Valuable Biomarker for Early Atherosclerosis in Rheumatoid Arthritis Patients: A Single‐Center Cross‐Sectional Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Hypercoagulability contributes to atherosclerosis (AS) progression in individuals suffering from rheumatoid arthritis (RA), and thromboelastography (TEG) is a valuable diagnostic tool. This hospital‐based cross‐sectional study assessed the clinical efficacy of TEG parameters in detecting hypercoagulability and subclinical AS by purposively ...
Qing‐Lin Zhang, Qian Xu, Rong Huang, Ming‐Zhong Sun, Dong‐Mei Jiang, Hui Tao, Hao Jin   +6 more
wiley   +1 more source

Enhancing Hemocompatibility in ECMO Systems With a Fibrinolytic Interactive Coating: in Vitro Evaluation of Blood Clot Lysis Using a 3D Microfluidic Model

Macromolecular Bioscience, EarlyView.
The functionalization of antifouling polymer brushes with tissue plasminogen activator resulted in a coating system that can direct blood components to digest blood clots in medical devices. This study further demonstrates the ability of this coating system to enhance clot‐lysis in fluid dynamic conditions that are close to the ones in extracorporeal ...
Lena Witzdam, Samarth Sandhu, Suji Shin, Yeahwa Hong, Shanzeh Kamal, Oliver Grottke, Keith E. Cook, Cesar Rodriguez‐Emmenegger   +7 more
wiley   +1 more source

A Novel Series of Synthetic Heparin‐Mimetics–Itaconic Acid‐Containing Copolymers for Targeting Tumor Cell Coagulability and Metastasis

Macromolecular Bioscience, EarlyView.
Heparin is postulated to possess antitumor properties‐ beyond its anticoagulative activities in oncology, but disclosure of targeted activities is complicated by heparins structural variabilities as natural glycosaminoglycans. Here, synthetic noncarbohydrate polymers are presented with tuneable structures as heparin mimetics in in‐vitro‐approaches for ...
Katrin Nekipelov, Abdullah Al Nahain, Sven Otto, Yongbin Xu, Jin‐Ping Li, Natasha Letunica, Simon Collett, Chantal Attard, Paul Monagle, George Vamvounis, John Tsanaktsidis, Vito Ferro, Gerd Bendas   +12 more
wiley   +1 more source

Severe hyperferremia and hyperferritinemia in a dog with precursor‐directed immune‐mediated anemia

Veterinary Clinical Pathology, Volume 51, Issue 4, Page 491-494, December 2022., 2022
Abstract A 4‐year‐old dog was evaluated at the Colorado State University Veterinary Teaching Hospital for lethargy and hyporexia of 24 hours duration. On presentation, she had a marked normocytic, normochromic, nonregenerative anemia (HCT 14%; RI 40–55).
Kristin M. Zersen, Carly W. Gregory, Christina M. Jeffries, Christine Olver   +3 more
wiley   +1 more source