Results 11 to 20 of about 4,243,823 (319)

Scalable carbon dioxide electroreduction coupled to carbonylation chemistry

open access: yesNature Communications, 2017
Electroreduction of CO2 to CO is a potential valorisation pathway of carbon dioxide for fine chemicals production. Here, the authors show a user-friendly device that couples CO2 electroreduction with carbonylation chemistry for up to gram scale synthesis
Mikkel T. Jensen   +8 more
doaj   +1 more source

Myosin IIa Promotes Antibody Responses by Regulating B Cell Activation, Acquisition of Antigen, and Proliferation

open access: yesCell Reports, 2018
Summary: B cell responses are regulated by antigen acquisition, processing, and presentation to helper T cells. These functions are thought to depend on contractile activity of non-muscle myosin IIa.
Robbert Hoogeboom   +6 more
doaj   +1 more source

An unexpected twist to the activation of IKKβ:TAK1 primes IKKβ for activation by autophosphorylation [PDF]

open access: yes, 2014
IKKß {IkB [inhibitor of NF-?B (nuclear factor ?B)] kinase ß} is required to activate the transcription factor NF-?B, but how IKKß itself is activated in vivo is still unclear.
Lawrence, T.   +9 more
core   +1 more source

Development of a novel light-up probe for detection of G-quadruplexes in stress granules

open access: yesScientific Reports, 2022
G-quadruplexes (G4s) regulate various biological processes in cells. However, cellular imaging of dynamically forming G4s in biomolecular condensates using small molecules has been poorly investigated. Herein, we present a fluorescent light-up probe with
Keisuke Iida   +4 more
doaj   +1 more source

Assisted Oocyte Activation Method (Ca ACTIVATION) Improves Fertilization in Patients with Recurrent Fertilization Failure

open access: yes, 2022
: Total fertilization failure (TFF) happens in 1–3% of total intracytoplasmic sperm injection (ICSI) cycles and may reoccur in sequent cycles. Regardless the high success rate with the applying of intracytoplasmic sperm injection (ICSI), there's still a ...
Mohammed H. Sayed Ahmad   +2 more
core   +1 more source

Cooperative redox activation for carbon dioxide conversion

open access: yesNature Communications, 2016
While CO2 can be converted to CO for further reactivity, typically this involves the generation of large amounts of waste. Here the authors report the conversion of CO2to CO, with the siloxane by-product being further used in a carbonylative Hiyama ...
Zhong Lian   +4 more
doaj   +1 more source

Voluntary activation of human knee extensors measured using transcranial magnetic stimulation [PDF]

open access: yes, 2009
The aim of this study was to determine the applicability and reliability of a transcranial magnetic stimulation twitch interpolation technique for measuring voluntary activation of a lower limb muscle group.
Ross, Emma   +10 more
core   +1 more source

Tethering of vesicles to the Golgi by GMAP210 controls LAT delivery to the immune synapse

open access: yesNature Communications, 2019
The immune synapse at the interface between T cells and antigen-presenting cells manifests intense vesicular trafficking, but how the vesicles are sorted is still unclear.
Andres Ernesto Zucchetti   +10 more
doaj   +1 more source

Not All Immune Checkpoints Are Created Equal

open access: yesFrontiers in Immunology, 2018
Antibodies that block T cell inhibition via the immune checkpoints CTLA-4 and PD-1 have revolutionized cancer therapy during the last 15 years. T cells express additional inhibitory surface receptors that are considered to have potential as targets in ...
Annika De Sousa Linhares   +3 more
doaj   +1 more source

FcγR requirements and costimulatory capacity of Urelumab, Utomilumab, and Varlilumab

open access: yesFrontiers in Immunology, 2023
IntroductionTargeting costimulatory receptors of the tumor necrosis factor receptor (TNFR) superfamily with agonistic antibodies is a promising approach in cancer immuno therapy.
Judith Leitner   +4 more
doaj   +1 more source

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