Results 11 to 20 of about 4,711,403 (316)
Activated: Decentering activism in and with academia [PDF]
Who is an activist? With the advent of activism-related scholarship in HCI and CSCW, the current challenge involves thinking about what activism is, who an activist is, and the opportunities and limitations of activism. Recently, researchers in academia and industry, such as Timnit Gebru, demonstrate a commitment to stay activated for the structural ...
Minha Lee +4 more
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To Activate or Not to Activate [PDF]
In a recent study, Watanabe et al identify a novel enhancer in the fgf10 locus that is necessary and sufficient for expression in anterior second heart field. Their results suggest a competitive mechanism in which Isl1 and Nkx2-5 bind the enhancer to activate or repress this enhancer, respectively.
Cornelis J, Boogerd, Sylvia M, Evans
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Activate or Not: Learning Customized Activation [PDF]
We present a simple, effective, and general activation function we term ACON which learns to activate the neurons or not. Interestingly, we find Swish, the recent popular NAS-searched activation, can be interpreted as a smooth approximation to ReLU. Intuitively, in the same way, we approximate the more general Maxout family to our novel ACON family ...
Ningning Ma +3 more
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Molecular brakes regulating mTORC1 activation in skeletal muscle following synergist ablation [PDF]
The goal of the current work was to profile positive (mTORC1 activation, autocrine/paracrine growth factors) and negative [AMPK, unfolded protein response (UPR)] pathways that might regulate overload-induced mTORC1 activation with the hypothesis that a ...
Hamilton, D. Lee +20 more
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Hydrogen is a widely used reductive reagent in organic synthesis. The direct reactions between dihydrogen and other organic compounds are very difficult, due to the high stability of hydrogen molecules.
Xinchen, HE +3 more
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Transcriptional activators and activation mechanisms [PDF]
Transcriptional activators are required to turn on the expression of genes in a eukaryotic cell. Activators bound to the enhancer can facilitate either the recruitment of RNA polymerase II to the promoter or its elongation. This article examines a few selected issues in understanding activator functions and activation mechanisms.
openaire +2 more sources
An unexpected twist to the activation of IKKβ:TAK1 primes IKKβ for activation by autophosphorylation [PDF]
IKKß {IkB [inhibitor of NF-?B (nuclear factor ?B)] kinase ß} is required to activate the transcription factor NF-?B, but how IKKß itself is activated in vivo is still unclear.
Lawrence, T. +9 more
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Voluntary activation of human knee extensors measured using transcranial magnetic stimulation [PDF]
The aim of this study was to determine the applicability and reliability of a transcranial magnetic stimulation twitch interpolation technique for measuring voluntary activation of a lower limb muscle group.
Ross, Emma +10 more
core +1 more source
: Total fertilization failure (TFF) happens in 1–3% of total intracytoplasmic sperm injection (ICSI) cycles and may reoccur in sequent cycles. Regardless the high success rate with the applying of intracytoplasmic sperm injection (ICSI), there's still a ...
Mohammed H. Sayed Ahmad +2 more
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Not All Immune Checkpoints Are Created Equal
Antibodies that block T cell inhibition via the immune checkpoints CTLA-4 and PD-1 have revolutionized cancer therapy during the last 15 years. T cells express additional inhibitory surface receptors that are considered to have potential as targets in ...
Annika De Sousa Linhares +3 more
doaj +1 more source

