Results 31 to 40 of about 4,243,823 (319)

HIV Patients Treated with Low-dose Prednisolone Exhibit Lower Immune Activation than Untreated Patients. [PDF]

, 2012
HIV-associated general immune activation is a strong predictor for HIV disease progression, suggesting that chronic immune activation may drive HIV pathogenesis. Consequently, immunomodulating agents may decelerate HIV disease progression.
Schmidt, Barabara, Albrecht Ulmer, Norbert Donhauser, Hartwig Klinker, Scheller Carsten, Scheller, Carsten, Kasang Christa, Barbara Schmidt, Stich, August, Schmidt, Barbara, Koutsilieri, Eleni, Ulmer Albrecht, Kalluvya, Samuel, Donhauser Norbert, Koutsilieri Eleni, Kalluvya Samuel, Klinker, Hartwig, Rethwilm, Axel, Axel Rethwilm, August Stich, Schmidt Barbara, Christa Kasang, Stich August, Ulmer, Albrecht, Klinker Hartwig, Samuel Kalluvya, Carsten Scheller, Donhauser, Norbert, Rethwilm Axel, Eleni Koutsilieri, Kasang, Christa   +30 more
core   +1 more source

The Impact of Knowledge About Business Model Canvas (BMC) on Entrepreneurial Interest of Young Generation in Jabodetabek

Indonesian Journal of Business and Entrepreneurship
This research aims to investigate the influence of Business Model Canvas (BMC) knowledge on entrepreneurial knowledge among young generations in the Jabodetabek region.
Nur Hendrasto, Fauziah Chairiyati, Abdullah Haidar, Evania Herindar, Hafiz Mudassir Rehman   +4 more
doaj   +1 more source

New Directions in Transition Metal Catalyzed Carbonylation Chemistry

CHIMIA, 2018
Carbon monoxide (CO) represents an important C1-building block for the construction of some of the most fundamental chemical functionalities carrying a carbon–oxygen double bond.
Dennis U. Nielsen, Karoline T. Neumann, Troels Skrydstrup   +2 more
doaj   +1 more source

Deep evolutionary conservation of an intramolecular protein kinase activation mechanism [PDF]

, 2012
DYRK-family kinases employ an intramolecular mechanism to autophosphorylate a critical tyrosine residue in the activation loop. Once phosphorylated, DYRKs lose tyrosine kinase activity and function as serine/threonine kinases.
Cleghon Vaughn, Aman Singh (191216), Cleghon, V., Nathan Luebbering (191210), Sibbet Gary, Jingfen Han, Luebbering Nathan, Nathan Luebbering, Michael A J Ferguson, Singh, A., Aman Singh, Ferguson, M.A.J., Ferguson Michael A. J., Hong, W., Diego Miranda-Saavedra (36622), Michael A. J. Ferguson (166662), Jingfen Han, Han, J., Gary Sibbet (191221), Vaughn Cleghon (191224), Miranda-Saavedra Diego, Sibbet, G., Ferguson, M.A.J.; id_orcid, Han Jingfen, Miranda-Saavedra, D., Gary Sibbet, Luebbering, N., Diego Miranda-Saavedra, Michael A. J. Ferguson, Vaughn Cleghon, Singh Aman, Jingfen Han (191204)   +31 more
core   +1 more source

Activation of Hydrogen

, 2022
Hydrogen is a widely used reductive reagent in organic synthesis. The direct reactions between dihydrogen and other organic compounds are very difficult, due to the high stability of hydrogen molecules.
Xinchen, HE, Yi, CHEN, Quoc Bao, Pham, Yuyao, GUO   +3 more
core   +1 more source

A Mouse Model to Study the Pathogenesis of γ-herpesviral Infections in Germinal Center B Cells

Cells, 2023
CD30-positive germinal center (GC)-derived B cell lymphomas are frequently linked to Epstein–Barr Virus (EBV) infection. However, a suitable animal model for the investigation of the interplay between γ-herpesvirus and host cells in B cell pathogenesis ...
Ursula Rambold, Stefanie Sperling, Zakir Chew, Yan Wang, Beatrix Steer, Krisztina Zeller, Lothar J. Strobl, Ursula Zimber-Strobl, Heiko Adler   +8 more
doaj   +1 more source

The Leech Nervous System: A Valuable Model to Study the Microglia Involvement in Regenerative Processes

Clinical and Developmental Immunology, 2013
Microglia are intrinsic components of the central nervous system (CNS). During pathologies in mammals, inflammatory processes implicate the resident microglia and the infiltration of blood cells including macrophages.
Françoise Le Marrec-Croq, Francesco Drago, Jacopo Vizioli, Pierre-Eric Sautière, Christophe Lefebvre   +4 more
doaj   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Direct π-Activation vs. O-Activation in Halogen Bonding Catalysis

, 2023
Halogen bond donors had an increasing impact on catalysis in recent years, and their development is highly active. In particular, numerous iodine-based halogen bond donors have been developed and used to promote various reactions through coordinating ...
Claude, Legault, Raphaël, Robidas
core   +1 more source

A Highly Sensitive Cell-Based TLR Reporter Platform for the Specific Detection of Bacterial TLR Ligands

Frontiers in Immunology, 2022
Toll-like receptors (TLRs) are primary pattern recognition receptors (PRRs), which recognize conserved microbial components. They play important roles in innate immunity but also in the initiation of adaptive immune responses.
Katharina Radakovics, Claire Battin, Judith Leitner, Sabine Geiselhart, Wolfgang Paster, Johannes Stöckl, Karin Hoffmann-Sommergruber, Peter Steinberger   +7 more
doaj   +1 more source