Results 41 to 50 of about 4,711,403 (316)

A Highly Sensitive Cell-Based TLR Reporter Platform for the Specific Detection of Bacterial TLR Ligands

open access: yesFrontiers in Immunology, 2022
Toll-like receptors (TLRs) are primary pattern recognition receptors (PRRs), which recognize conserved microbial components. They play important roles in innate immunity but also in the initiation of adaptive immune responses.
Katharina Radakovics   +7 more
doaj   +1 more source

Biphasic Clinical Course of Pediatric Cytomegalovirus‐Associated Immune Thrombocytopenia: Early Poor Treatment Response but Favorable Long‐Term Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad   +9 more
wiley   +1 more source

Bone Mineral Density After Contemporary Treatment for Acute Lymphoblastic Leukaemia: A Matched Cross‐Sectional Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen   +10 more
wiley   +1 more source

Non-canonical activation of PI3Kγ by Ca²⁺/PKCβ in mast cells [PDF]

open access: yes, 2014
Mast cells are key effector cells in allergic disease triggering inflammation through mediator release. Allergens activate mast cells through the high-affinity receptor for IgE (FcεRI), which initiates signalling pathways that regulate the release of
Walser, Romy
core   +1 more source

Inter-agency co-operation in activation: comparing three vanguard ‘active’ welfare states [PDF]

open access: yes, 2008
New forms of inter-agency co-operation have gained increasing prominence in the development and delivery of activation strategies. This article compares different models of inter-agency co-operation, drawing on case study research in Denmark, the ...
Lindsay, Colin, McQuaid, Ronald
core   +2 more sources

Elevated Dengue Virus Nonstructural Protein 1 Serum Levels and Altered Toll-Like Receptor 4 Expression, Nitric Oxide, and Tumor Necrosis Factor Alpha Production in Dengue Hemorrhagic Fever Patients

open access: yesJournal of Tropical Medicine, 2014
Background. During dengue virus (DV) infection, monocytes produce tumor necrosis factor alpha (TNF-α) and nitric oxide (NO) which might be critical to immunopathogenesis.
Denise Maciel Carvalho   +6 more
doaj   +1 more source

Charcoal Activation [PDF]

open access: yesProceedings of the National Academy of Sciences, 1919
Adsorption of Gases by Charcoal—Heat Effect.—The first part of this paper comprises a study of the heat effect on the adsorption of hydrogen and nitrogen by charcoal, and is a continuation of the work of Dr. Harvey B. Lemon1 in which air was used. The charcoal is heated for periods varying from one hour to twenty hours at temperatures from 400° C.
openaire   +4 more sources

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko   +5 more
wiley   +1 more source

Actively Seeking Activating Sequences [PDF]

open access: yesCell, 2004
I thank R. Brent, I. Cartwright, L. Keegan, Z. Liu, M. Ptashne, and M. Xu for comments. I apologize that the page limit did not permit citation of all relevant work. This work was supported in part by the AHA and the NSF.
openaire   +2 more sources

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess   +5 more
wiley   +1 more source

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