Results 51 to 60 of about 6,318,056 (279)
Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma
ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano +7 more
wiley +1 more source
First Results on Moss Biomonitoring of Trace Elements in the Central Part of Georgia, Caucasus
The moss biomonitoring technique was used for assessment of air pollution in the central part of Georgia, Caucasus, in the framework of the UNECE ICP Vegetation.
Omari Chaligava +7 more
doaj +1 more source
Ampk regulates IgD expression but not energy stress with B cell activation. [PDF]
Ampk is an energy gatekeeper that responds to decreases in ATP by inhibiting energy-consuming anabolic processes and promoting energy-generating catabolic processes.
Ahsan, Fasih M +9 more
core +1 more source
Knowledge Transfer via Distillation of Activation Boundaries Formed by Hidden Neurons
An activation boundary for a neuron refers to a separating hyperplane that determines whether the neuron is activated or deactivated. It has been long considered in neural networks that the activations of neurons, rather than their exact output values ...
Choi, Jin Young +3 more
core +1 more source
ABSTRACT Although most malignant germ cell tumors (GCTs) are highly curable with cisplatin‐based therapy, options for patients with multiply relapsed/refractory disease remain limited. For this population, we report the first pediatric use of gemcitabine, docetaxel, melphalan, and carboplatin (GemDMC) as part of sequential cycles of high‐dose ...
Maria Frost +10 more
wiley +1 more source
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack +39 more
wiley +1 more source
Background. During dengue virus (DV) infection, monocytes produce tumor necrosis factor alpha (TNF-α) and nitric oxide (NO) which might be critical to immunopathogenesis.
Denise Maciel Carvalho +6 more
doaj +1 more source
Bound non-locality and activation
We investigate non-locality distillation using measures of non-locality based on the Elitzur-Popescu-Rohrlich decomposition. For a certain number of copies of a given non-local correlation, we define two quantities of interest: (i) the non-local cost ...
Alejo Salles +4 more
core +1 more source
A major function of platelets is keeping the vascular system intact. Platelet activation at sites of vascular injury leads to the formation of a hemostatic plug.
Schattner, Mirta Ana
core +1 more source
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa +3 more
wiley +1 more source

