Results 141 to 150 of about 17,207,076 (361)

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Graphene/silicon heterojunction for reconfigurable phase-relevant activation function in coherent optical neural networks. [PDF]

Nat Commun, 2023
Zhong C, Liao K, Dai T, Wei M, Ma H, Wu J, Zhang Z, Ye Y, Luo Y, Chen Z, Jian J, Sun C, Tang B, Zhang P, Liu R, Li J, Yang J, Li L, Liu K, Hu X, Lin H.   +20 more
europepmc   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Improving Surgical Scene Semantic Segmentation through a Deep Learning Architecture with Attention to Class Imbalance

Biomedicines
This article addresses the semantic segmentation of laparoscopic surgery images, placing special emphasis on the segmentation of structures with a smaller number of observations.
Claudio Urrea, Yainet Garcia-Garcia, John Kern   +2 more
doaj   +1 more source

Dynamical Isometry is Achieved in Residual Networks in a Universal Way for any Activation Function

, 2019
We demonstrate that in residual neural networks (ResNets) dynamical isometry is achievable irrespectively of the activation function used. We do that by deriving, with the help of Free Probability and Random Matrix Theories, a universal formula for the ...
Jastrzębski, Stanisław, Nowak, Maciej A., Tabor, Jacek, Tarnowski, Wojciech, Warchoł, Piotr   +4 more
core  

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Radar Signal Recognition Based on CSRDNN Network

IEEE Access
It is essential to achieve the high-accuracy recognition of low probability of intercept (LPI) radar signals in modern electronic warfare. However, under low signal-to-noise ratio (SNR), the recognition accuracy of the LPI radar signals is relatively low.
Zheng Zhang, Chuan Wan, Yi Chen, Fang Zhou, Xiaofei Zhu, Wenchao Zhai, Daying Quan   +6 more
doaj   +1 more source

A Novel Image Classification Method Based on Residual Network, Inception, and Proposed Activation Function. [PDF]

Sensors (Basel), 2023
Yahya AA, Liu K, Hawbani A, Wang Y, Hadi AN.   +4 more
europepmc   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Molecular determinants of complexin clamping and activation function. [PDF]

Elife, 2022
Bera M, Ramakrishnan S, Coleman J, Krishnakumar SS, Rothman JE.   +4 more
europepmc   +1 more source