Results 91 to 100 of about 5,159,180 (362)

Stk38 protein kinase preferentially inhibits TLR9-activated inflammatory responses by promoting MEKK2 ubiquitination in macrophages [PDF]

open access: gold, 2015
Mingyue Wen   +12 more
openalex   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Ephalometrıc Evaluatıon Of The Immedıate Changes In Cervıcal Structures After The Applıcatıon Of The Actıvator

open access: yesTurkish Journal of Orthodontics, 1990
This study was accomplished to determine the 'postural adaptations of the structures related to cervical vertebrae, after changing the functional conditions with the activator.
Rüştiye Sürücü   +2 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Effects of the Activator and Twin Block on Facial Soft Tissue Thickness in Class II Division 1 Patients

open access: yesTurkish Journal of Orthodontics, 2014
Objective:The purpose of this study was to evaluate and compare the effects of the activator and Twin Block appliances on soft tissue thickness in Class II division 1 patients.Materials and Methods:Soft tissue thickness measurements were obtained from ...
Mehmet Akın   +3 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

The Treatment Effects Of Open-Bıte Cases Wıth Combınatıon Of Actıvator, Occıpıtal Headgear, And Vertıcal Chın-Cap On Soft Tıssue Profıle

open access: yesTurkish Journal of Orthodontics, 1997
This study was held on totally 68 lateral cephalograins and hand-wrist radiograms of 34 individuals. The materials of this study were obtained from the individuals at the beginning and at the end of treatment and controls.
Zahir Altuğ, Meliha Rübendüz
doaj   +1 more source

Stimulation of P-selectin glycoprotein ligand-1 on mouse neutrophils activates β2 -integrin mediated cell attachment to ICAM-1 [PDF]

open access: bronze, 1998
James E. Blanks   +3 more
openalex   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

The Evaluatıon Of Facıal Profıle Changes In Indıvıduals Wıth Skeletal Class Iı Anomaly Treated Wıth Actıvator And Actıvator + Occıpıtal Headgear

open access: yesTurkish Journal of Orthodontics, 1989
The aim of this study is to evaluate the changes occuring in facial profile in individuals treated with activator and activator + occipital headgear. Our study is based on two treatment groups namely activator and activator + occipital headgear and one ...
Hakan Gögen, Şebnem Parlar
doaj   +1 more source

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