Results 41 to 50 of about 1,292,062 (304)
Optimizing periodicity and polymodality in noise-induced genetic oscillators [PDF]
, 2011 Many cellular functions are based on the rhythmic organization of biological processes into self-repeating cascades of events. Some of these periodic processes, such as the cell cycles of several species, exhibit conspicuous irregularities in the form of
A. Sveiczer +6 more
core +3 more sources
Validation of Hv1 channel functions in BV2 microglial cells using small molecule modulators
Frontiers in Cellular NeuroscienceMicroglia are the first responders to insults or damages in the brain where they display both beneficial and detrimental effects. Excessively activated microglia aggravate the secondary damage by producing several proinflammatory mediators. Voltage-gated
Ashutosh Sharma +12 more
doaj +1 more source
AN INFLUENCE OF THE d311 EFFECT ON THE BEHAVIOR OF THE CANTILEVER BEAM-SHAPED PIEZOELECTRIC ACTIVATOR MADE OF TWO LAYERS OF PVDF WITH INVERSE POLARITY [PDF]
Applied Computer Science, 2014 In the present work an example of the numerical modeling of electro-mechanical coupling of the activator in the form of cantilever beam made of two layers PVDF subjected to an inverse polarity is described.
Andrzej TETER +2 more
doaj
Activators and Inhibitors of Protein Kinase C (PKC): Their Applications in Clinical Trials
Pharmaceutics, 2021 Protein kinase C (PKC), a family of phospholipid-dependent serine/threonine kinase, is classed into three subfamilies based on their structural and activation characteristics: conventional or classic PKC isozymes (cPKCs; α, βI, βII, and γ), novel or non ...
Takahito Kawano +4 more
doaj +1 more source
Finding the center reliably: robust patterns of developmental gene expression
, 2005 We investigate a mechanism for the robust identification of the center of a developing biological system. We assume the existence of two morphogen gradients, an activator emanating from the anterior, and a co-repressor from the posterior.
A. Eldar +9 more
core +1 more source
Management of hardening mixtures properties when stowing mining sites of ore deposits
Записки Горного института, 2020 Underground mining is characterized by the weakening of the bearing rock mass strata competence and the accumulation of mineral waste. The full use of subsurface resources is ensured by the use of technologies with filling voids by hardening mixtures ...
Vladimir I. Golik +3 more
doaj +1 more source
Structure–Activity Studies on Bis-Sulfonamide SHIP1 Activators
Molecules, 2023 The SH2-containing inositol polyphosphate 5-phosphatase 1 (SHIP1) enzyme opposes the activity of PI3K and therefore is of interest in the treatment of inflammatory disorders.
Shea T. Meyer +6 more
doaj +1 more source
Engineering orthogonal dual transcription factors for multi-input synthetic promoters [PDF]
, 2016 Synthetic biology has seen an explosive growth in the capability of engineering artificial gene circuits from transcription factors (TFs), particularly in bacteria. However, most artificial networks still employ the same core set of TFs (for example LacI,
Broedel, AK, Isalan, M, Jaramillo, A
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Neuroblastoma is the most common extracranial solid tumor in early childhood. Its clinical behavior is highly variable, ranging from spontaneous regression to fatal outcome despite intensive treatment. The International Society of Pediatric Oncology Europe Neuroblastoma Group (SIOPEN) Radiology and Nuclear Medicine Specialty Committees ...
Annemieke Littooij +11 more
wiley +1 more source
ChemElectroChem, 2023 Low cost and environmentally friendly production of graphite anodes from naturally available biomass resources is of great importance to satisfy the increasing material demand for lithium ion batteries.
Lars Frankenstein +5 more
doaj +1 more source