Results 11 to 20 of about 4,610,135 (394)
The dawn of active genetics [PDF]
BioEssays, 2015 On December 18, 2014, a yellow female fly quietly emerged from her pupal case. What made her unique was that she had only one parent carrying a mutant allele of this classic recessive locus.
Valentino M, Gantz, Ethan, Bier
openaire +2 more sources
Genetics of plasma paroxonase activity [PDF]
Journal of Medical Genetics, 1982 Complex segregation analysis of plasma paroxonase activity gives evidence for a major locus with incomplete dominance (d = 0·70) causing high activity plus a background of multifactorial inheritance (heritability = 0·09).
L, Iselius, D A, Evans, J R, Playfer
openaire +2 more sources
The Genetic Activity Profile Database [PDF]
Environmental Health Perspectives, 1991 A graphic approach termed a Genetic Activity Profile (GAP) has been developed to display a matrix of data on the genetic and related effects of selected chemical agents. The profiles provide a visual overview of the quantitative (doses) and qualitative (test results) data for each chemical.
M D, Waters +3 more
openaire +3 more sources
Genetic activity during early plant embryogenesis [PDF]
Biochemical Journal, 2020 Seeds are essential for human civilization, so understanding the molecular events underpinning seed development and the zygotic embryo it contains is important. In addition, the approach of somatic embryogenesis is a critical propagation and regeneration strategy to increase desirable genotypes, to develop new genetically modified plants to meet ...
Ran Tian +3 more
openaire +2 more sources
Genetic control of active neural circuits [PDF]
Frontiers in Molecular Neuroscience, 2009 The use of molecular tools to study the neurobiology of complex behaviors has been hampered by an inability to target the desired changes to relevant groups of neurons. Specific memories and specific sensory representations are sparsely encoded by a small fraction of neurons embedded in a sea of morphologically and functionally similar cells.
Leon Reijmers +3 more
openaire +3 more sources
iScience, 2018 Summary: TUC338 is an ultraconserved long non-coding RNA that contributes to transformed cell growth in hepatocellular carcinoma (HCC). Genomic regions of TUC338 occupancy were enriched in unique or known binding motifs homologous to the tumor ...
Hui-Ju Wen +5 more
doaj +1 more source
Target identification strategies in plant chemical biology [PDF]
, 2014 The current needs to understand gene function in plant biology increasingly require more dynamic and conditional approaches opposed to classic genetic strategies.
Dejonghe, Wim, Russinova, Eugenia
core +2 more sources
EBioMedicine, 2023 Summary: Background: Identifying new drug targets for inflammatory bowel disease (IBD) is urgently needed. The proteome is a major source of therapeutic targets.
Jie Chen +11 more
doaj +1 more source
Intrinsic limits to gene regulation by global crosstalk [PDF]
, 2016 Gene regulation relies on the specificity of transcription factor (TF) - DNA interactions. In equilibrium, limited specificity may lead to crosstalk: a regulatory state in which a gene is either incorrectly activated due to noncognate TF-DNA interactions
Barton, Nicholas H. +4 more
core +4 more sources
PLoS Genetics, 2015 Natural disasters, including drought and salt stress, seriously threaten food security. In previous work we cloned a key zinc finger transcription factor gene, Drought and Salt Tolerance (DST), a negative regulator of drought and salt tolerance that ...
Longgang Cui +4 more
semanticscholar +1 more source