Results 191 to 200 of about 3,963,692 (395)

Peroxisome Proliferator-Activated Receptor-γ Calls for Activation in Moderation: Lessons from Genetics and Pharmacology [PDF]

, 2004
Chris Knouff, Johan Auwerx
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Cancer Genetics: Activated Notch takes center stage in T-cell leukemogenesis [PDF]

, 2005
Mark Y. Chiang, Warren S. Pear
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Intersection of population variation and autoimmunity genetics in human T cell activation

, 2014
C. J. Ye, Ting Feng, Ho‐Keun Kwon, Towfique Raj, Michael T. Wilson, Natasha Asinovski, Cristin McCabe, M. H. Lee, I. Fröhlich, Hyun-il Paik, Noah Zaitlen, Nir Hacohen, Barbara E. Stranger, Philip L. De Jager, Diane Mathis, Christophe Benoıst, Aviv Regev   +16 more
openalex   +3 more sources

Author Correction: Disentangling the architectural and non-architectural functions of CTCF and cohesin in gene regulation. [PDF]

Nat Genet
Narita T, Kilic S, Higashijima Y, Scherer NM, Pappas G, Maskey E, Choudhary C.   +6 more
europepmc   +1 more source

Interstitial stem cells in Hydra [PDF]

, 1987
Bosch, Thomas C. G., David, Charles N., Hobmayer, Engelbert, Holstein, Thomas W., Loomis, W. F., Schmidt, Tobias   +5 more
core  

Chemical genetics reveals cross-activation of plant developmental signaling by the immune peptide-receptor pathway [PDF]

Arvid Herrmann, Krishna Mohan Sepuru, Hitoshi Endo, Ayami Nakagawa, Shuhei Kusano, Pengfei Bai, Asraa Ziadi, Hiroe Kato, Ayato Sato, Jun O. Liu, Libo Shan, Seisuke Kimura, Kenichiro Itami, Naoyuki Uchida, Shinya Hagihara, Keiko U. Torii   +15 more
openalex   +1 more source

Genetics reveals importance of platelet activating factor in asthma and possibly other inflammatory states. [PDF]

, 1996
Jay A. Nadel
openalex   +1 more source