Results 221 to 230 of about 3,963,692 (395)

Physiological and gene expression analysis of Hevea brasiliensis under drought stress. [PDF]

PLoS One
Mohammadi Nodehi M, Mahmoudieh M, Taleei A, Mohammadi V, Rahman MM, Zargar M, Naghavi MR.   +6 more
europepmc   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

An Update on Post-infectious Irritable Bowel Syndrome: Role of Genetics, Immune Activation, Serotonin and Altered Microbiome

, 2012
Robert E. Spiller, Ching Lam
openalex   +2 more sources

Peroxisome Proliferator-Activated Receptor-δ Genotype Influences Metabolic Phenotype and May Influence Lipid Response to Statin Therapy in Humans: A Genetics of Diabetes Audit and Research Tayside Study [PDF]

, 2010
Lindsay Burch, Louise A. Donnelly, Alex S. F. Doney, Jeffrey D. Brady, Anna Tommasi, Adrian L. Whitley, Catharine A. Goddard, Andrew D. Morris, Michael K. Hansen, Colin N. A. Palmer   +9 more
openalex   +1 more source

The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis.

Human Molecular Genetics, 2005
Jin Xu, N. Zhong, Haoyong Wang, Joshua E. Elias, Christina Y Kim, I. Woldman, C. Pifl, S. Gygi, C. Geula, B. Yankner   +9 more
semanticscholar   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Author Correction: The kinase TNIK is an essential activator of Wnt target genes. [PDF]

EMBO J
Mahmoudi T, Li VSW, Ng SS, Taouatas N, Vries RGJ, Mohammed S, Heck AJ, Clevers H.   +7 more
europepmc   +1 more source

The genetics of schizophrenia : the contribution of common variants and genes implicated in a maternal immune activation model

, 2016
Shing-wan Choi
openalex   +1 more source

Epistatic Interactions between Opaque2 Transcriptional Activator and Its Target Gene CyPPDK1 Control Kernel Trait Variation in Maize1[C][W][OA]

Plant Physiology, 2009
D. Manicacci, L. Camus-Kulandaivelu, M. Fourmann, C. Arar, S. Barrault, A. Rousselet, Noël Feminias, L. Consoli, Lisa Francès, V. Méchin, A. Murigneux, J. Prioul, A. Charcosset, C. Damerval   +13 more
semanticscholar   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source