Results 231 to 240 of about 260,779 (356)

Identification of a Novel Mutation in the SERPINE1 Gene Causing Clinical Hyperfibrinolysis in English Springer Spaniel Dogs. [PDF]

J Vet Intern Med
Kilpatrick K, Cullen JN, Almeer FF, Higgins L, Markowski T, Brooks M, Friedenberg SG, Racette M.   +7 more
europepmc   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Editorial: Exploring structural variants in plant pangenomics: innovations and applications. [PDF]

Front Plant Sci
Wang J, Zhou Q, Liu Y, Li R, Lan L, Zhao J, Yang Z, Jia Y, Hu H.   +8 more
europepmc   +1 more source

Macrophage activation syndrome as part of systemic juvenile idiopathic arthritis: diagnosis, genetics, pathophysiology and treatment

, 2012
Angelo Ravelli, Alexei A. Grom, Edward M. Behrens, Randy Q. Cron   +3 more
openalex   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

Molecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa, Julia Richert, Tomasz Stokowy, Alicja Staśczak, Mariusz Szajewski, Maciej Ciesielski, Petra M. Grešner, Bartłomiej Tomasik, Łukasz Arcimowicz, Agnieszka Stankiewicz, Grażyna Suchodolska, Elżbieta Senkus, Wiesław Kruszewski, Anna J. Żaczek, Aleksandra Markiewicz   +14 more
wiley   +1 more source

TSSKL is essential for sperm mitochondrial morphogenesis and male fertility in moths. [PDF]

PLoS Genet
Xu X, Zhu L, Xu X, Chen J, Du X, Zhu L, Yu S, Qian L, Jiang X, Zhou L, Dong Y, Wang Y, Huang Y, Wang Y.   +13 more
europepmc   +1 more source

Medical genetics: advances in brief: Homology of a candidate spermatogenic gene from the mouse Y chromosome to the ubiquitin-activating enzyme E1

, 1992
Andrew O.M. Wilkie
openalex   +1 more source

The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity

Molecular Oncology, EarlyView.
Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause, Rixa‐Mareike Köhn, Christian Ickes, Julia Lenger, Jonas Fischer, Sabrina Cappello, Ivan Bogeski   +6 more
wiley   +1 more source

Viral oncogenes drive biphenotypic lymphoproliferative malignancy in transgenic mice. [PDF]

Sci Rep
Rauch DA, Harding J, Joseph A, Ratner L.
europepmc   +1 more source

Faculty Opinions recommendation of Activated PI3 kinase delta syndrome: from genetics to therapy.

, 2020
Larry Kane
openalex   +2 more sources