Results 21 to 30 of about 3,917,874 (426)

About Epizootic Situation on Major Helminthosis of Different Breeds of Pigs in Georgia

open access: yesРоссийский паразитологический журнал, 2020
The purpose of the research is to study the epizootic situation on major helminthosis of different breed groups of pigs in Georgia. Materials and methods.
L. M. Udzhmadzhuridze   +3 more
doaj   +1 more source

DCA1 Acts as a Transcriptional Co-activator of DST and Contributes to Drought and Salt Tolerance in Rice

open access: yesPLoS Genetics, 2015
Natural disasters, including drought and salt stress, seriously threaten food security. In previous work we cloned a key zinc finger transcription factor gene, Drought and Salt Tolerance (DST), a negative regulator of drought and salt tolerance that ...
Longgang Cui   +4 more
semanticscholar   +1 more source

Identification and characterization of a Mef2 transcriptional activator in schistosome parasites. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2012
Myocyte enhancer factor 2 protein (Mef2) is an evolutionarily conserved activator of transcription that is critical to induce and control complex processes in myogenesis and neurogenesis in vertebrates and insects, and osteogenesis in vertebrates.
John N Milligan, Emmitt R Jolly
doaj   +1 more source

Evolution of default genetic control mechanisms [PDF]

open access: yes, 2021
We present a model of the evolution of control systems in a genome under environmental constraints. The model conceptually follows the Jacob and Monod model of gene control. Genes contain control elements which respond to the internal state of the cell as well as the environment to control expression of a coding region.
arxiv   +1 more source

Anaplastic large cell lymphoma: pathology, genetics, and clinical aspects.

open access: yesJournal of Clinical and Experimental Hematopathology, 2017
Anaplastic large cell lymphoma (ALCL) was first described in 1985 as a large-cell neoplasm with anaplastic morphology immunostained by the Ki-1 antibody, which recognizes CD30.
N. Tsuyama   +4 more
semanticscholar   +1 more source

Sexual Dimorphism in Osteoclasts

open access: yesCells, 2020
Osteoclasts are the principal mediators of bone resorption. They form through the fusion of mononuclear precursor cells under the principal influence of the cytokines macrophage colony stimulating factor (M-CSF, aka CSF-1) and receptor activator of NF-κB
Joseph Lorenzo
doaj   +1 more source

The Cryptococcus neoformans Alkaline Response Pathway: Identification of a Novel Rim Pathway Activator

open access: yesPLoS Genetics, 2015
The Rim101/PacC transcription factor acts in a fungal-specific signaling pathway responsible for sensing extracellular pH signals. First characterized in ascomycete fungi such as Aspergillus nidulans and Saccharomyces cerevisiae, the Rim/Pal pathway ...
Kyla S. Ost   +5 more
semanticscholar   +1 more source

Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects

open access: yesSignal Transduction and Targeted Therapy, 2020
Based on engineered or bacterial nucleases, the development of genome editing technologies has opened up the possibility of directly targeting and modifying genomic sequences in almost all eukaryotic cells.
Hongyi Li   +5 more
semanticscholar   +1 more source

Dismantling a dogma: the inflated significance of neutral genetic diversity in conservation genetics [PDF]

open access: yes, 2020
The current rate of species extinction is rapidly approaching unprecedented highs and life on Earth presently faces a sixth mass extinction event driven by anthropogenic activity, climate change and ecological collapse. The field of conservation genetics aims at preserving species by using their levels of genetic diversity, usually measured as neutral ...
arxiv   +1 more source

The Overlapping and Distinct Roles of HAM Family Genes in Arabidopsis Shoot Meristems

open access: yesFrontiers in Plant Science, 2020
In Arabidopsis shoot apical meristems (SAMs), a well-characterized regulatory loop between WUSCHEL (WUS) and CLAVATA3 (CLV3) maintains stem cell homeostasis by regulating the balance between cell proliferation and cell differentiation.
Han Han   +13 more
doaj   +1 more source

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