Results 31 to 40 of about 260,779 (356)

Gene-Drug Interaction in Stroke

open access: yesStroke Research and Treatment, 2011
Stroke is the third cause of mortality and one of most frequent causes of long-term neurological disability, as well as a complex disease that results from the interaction of environmental and genetic factors.
Serena Amici   +3 more
doaj   +1 more source

Sequence analysis of the cis-regulatory regions of the bithorax complex of Drosophila [PDF]

open access: yes, 1995
The bithorax complex (BX-C) of Drosophila, one of two complexes that act as master regulators of the body plan of the fly, has now been entirely sequenced and comprises approximate to 315,000 bp, only 1.4% of which codes for protein.
Celniker, Susan E.   +3 more
core   +1 more source

Reaction diffusion processes on random and scale-free networks [PDF]

open access: yes, 2004
We study the discrete Gierer-Meinhardt model of reaction-diffusion on three different types of networks: regular, random and scale-free. The model dynamics lead to the formation of stationary Turing patterns in the steady state in certain parameter ...
De Wit A.   +4 more
core   +2 more sources

The genetical activity of heterochromatin [PDF]

open access: yesProceedings of the Royal Society of London. Series B - Biological Sciences, 1944
Heterochromatic supernumerary chromosomes in various plants differ from the chromosomes of the regular complement in not being essential to normal growth and survival. They cannot, however, be genetically inert for they have been shown to affect the fitness of plants carrying them.
openaire   +2 more sources

Dormancy Associated with Repression of Genetic Activity [PDF]

open access: yesPlant Physiology, 1964
Dormancy of buds and seeds is a well known and common phenomenon in the plant world. It is of interest because it has not yet become understandable. The dormant tissue has available to it by definition all of the environmental conditions of temperature, water supply, nutrition, etc., required for growth. The dormant tissue is alive, it respires,
Tuan, Dorothy Y. H., Bonner, James
openaire   +4 more sources

A secretory kinase complex regulates extracellular protein phosphorylation. [PDF]

open access: yes, 2015
Although numerous extracellular phosphoproteins have been identified, the protein kinases within the secretory pathway have only recently been discovered, and their regulation is virtually unexplored.
Cui, Jixin   +5 more
core   +2 more sources

Emerging patterns of genetic overlap across autoimmune disorders. [PDF]

open access: yes, 2012
Most of the recently identified autoimmunity loci are shared among multiple autoimmune diseases. The pattern of genetic association with autoimmune phenotypes varies, suggesting that certain subgroups of autoimmune diseases are likely to share ...
Criswell, Lindsey A   +1 more
core   +1 more source

Generation and characterization of keap1a- and keap1b-knockout zebrafish

open access: yesRedox Biology, 2020
The Keap1–Nrf2 pathway is an evolutionarily conserved mechanism that protects cells from oxidative stress and electrophiles. Under homeostatic conditions, Keap1 interacts with Nrf2 and leads to its rapid proteasomal degradation, but when cells are ...
Vu Thanh Nguyen   +6 more
doaj   +1 more source

The yeast PUF protein Puf5 has Pop2-independent roles in response to DNA replication stress. [PDF]

open access: yesPLoS ONE, 2010
PUFs are RNA binding proteins that promote mRNA deadenylation and decay and inhibit translation. Yeast Puf5 is the prototype for studying PUF-dependent gene repression.
Ana Traven   +3 more
doaj   +1 more source

From Science to Success? Targeting Tyrosine Kinase 2 in Spondyloarthritis and Related Chronic Inflammatory Diseases

open access: yesFrontiers in Genetics, 2021
Spondyloarthritis (SpA) is a family of inflammatory arthritic diseases, which includes the prototypes of psoriatic arthritis and ankylosing spondylitis.
Dominika Hromadová   +7 more
doaj   +1 more source

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