Results 41 to 50 of about 3,917,874 (426)

Use of the Iron-Responsive RBT5 Promoter for Regulated Expression in Candida albicans

mSphere, 2022
Engineered conditional gene expression is used in appraisal of gene function and pathway relationships. For pathogens like the fungus Candida albicans, conditional expression systems are most useful if they are active in the infection environment and if ...
Yinhe Mao, Norma V. Solis, Anupam Sharma, Max V. Cravener, Scott G. Filler, Aaron P. Mitchell   +5 more
doaj   +1 more source

Wnt, notch, and TGF-β pathways impinge on hedgehog signaling complexity: an open window on cancer [PDF]

, 2019
Constitutive activation of the Hedgehog (Hh) signaling pathway is associated with increased risk of developing several malignancies. The biological and pathogenic importance of Hh signaling emphasizes the need to control its action tightly, both ...
Bellavia, Diana, Checquolo, Saula, Nardozza, Francesca, Pelullo, Maria, Screpanti, Isabella, Zema, Sabrina   +5 more
core   +1 more source

Gene-Drug Interaction in Stroke

Stroke Research and Treatment, 2011
Stroke is the third cause of mortality and one of most frequent causes of long-term neurological disability, as well as a complex disease that results from the interaction of environmental and genetic factors.
Serena Amici, Maurizio Paciaroni, Giancarlo Agnelli, Valeria Caso   +3 more
doaj   +1 more source

Xenopus: An ideal system for chemical genetics [PDF]

, 2012
Chemical genetics, or chemical biology, has become an increasingly powerful method for studying biological processes. The main objective of chemical genetics is the identification and use of small molecules that act directly on proteins, allowing rapid ...
Adams, Adams, Almogy, Banaszynski, Blackiston, Blackiston, Brändli, Cambridge, Carneiro, Chae, Chang, Chen, Clark, Dale, Das, Davidson, Deiters, Dodd, Dupre, Dush, Fini, Frank-Kamenetsky, Fukumoto, Garcia-Morales, Goda, Grammer, Hanvey, Hartley, Heasman, Horb, Huang, Kalin, Kolm, Lennox, Levin, Liu, Liu, Liu, Longo, Love, Lund, Meijer, Morckel, Nielsen, Nusslein-Volhard, Obika, Paddison, Page-McCaw, Peterson, Peterson, Pownall, Rankin, Reya, Richards, Rones, Schneider, Shestopalov, Stankunas, Tomlinson, Tomlinson, Tomlinson, Tomlinson, Tomlinson, Van Raay, Vandenberg, Verma, Wahlestedt, Walsh, Wheeler, Wheeler, White, Wignall, Woolf, Yang   +73 more
core   +1 more source

The genetical activity of heterochromatin [PDF]

Proceedings of the Royal Society of London. Series B - Biological Sciences, 1944
Heterochromatic supernumerary chromosomes in various plants differ from the chromosomes of the regular complement in not being essential to normal growth and survival. They cannot, however, be genetically inert for they have been shown to affect the fitness of plants carrying them.
openaire   +2 more sources

Dormancy Associated with Repression of Genetic Activity [PDF]

Plant Physiology, 1964
Dormancy of buds and seeds is a well known and common phenomenon in the plant world. It is of interest because it has not yet become understandable. The dormant tissue has available to it by definition all of the environmental conditions of temperature, water supply, nutrition, etc., required for growth. The dormant tissue is alive, it respires,
Tuan, Dorothy Y. H., Bonner, James
openaire   +4 more sources

TALEN-Based Mutagenesis of Lipoxygenase LOX3 Enhances the Storage Tolerance of Rice (Oryza sativa) Seeds. [PDF]

PLoS ONE, 2015
The deterioration of rice grain reduces the quality of rice, resulting in serious economic losses for farmers. Lipoxygenases (LOXs) catalyze the dioxygenation of polyunsaturated fatty acids with at least one cis,cis-1,4-pentadiene to form hydroperoxide ...
Lei Ma, Fugui Zhu, Zhenwei Li, Jianfu Zhang, Xin Li, Jiangli Dong, Tao Wang   +6 more
doaj   +1 more source

Verticillium dahliae Vta3 promotes ELV1 virulence factor gene expression in xylem sap, but tames Mtf1-mediated late stages of fungus-plant interactions and microsclerotia formation.

PLoS Pathogens, 2023
Verticillium transcription activator of adhesion 3 (Vta3) is required for plant root colonization and pathogenicity of the soil-borne vascular fungus Verticillium dahliae.
Isabel Maurus, Rebekka Harting, Cornelia Herrfurth, Jessica Starke, Alexandra Nagel, Lennart Mohnike, Ying-Yu Chen, Kerstin Schmitt, Emmanouil Bastakis, Marian T Süß, Miriam Leonard, Kai Heimel, Oliver Valerius, Ivo Feussner, James W Kronstad, Gerhard H Braus   +15 more
doaj   +1 more source

The yeast PUF protein Puf5 has Pop2-independent roles in response to DNA replication stress. [PDF]

PLoS ONE, 2010
PUFs are RNA binding proteins that promote mRNA deadenylation and decay and inhibit translation. Yeast Puf5 is the prototype for studying PUF-dependent gene repression.
Ana Traven, Tricia L Lo, Trevor Lithgow, Jörg Heierhorst   +3 more
doaj   +1 more source

Do active nematic self-mixing dynamics help growing bacterial colonies to maintain local genetic diversity? [PDF]

arXiv, 2022
Recent studies have shown that packings of cells, both eukaryotic cellular tissues and growing or swarming bacterial colonies, can often be understood as active nematic fluids. A key property of volume-conserving active nematic model systems is chaotic self-mixing characterized by motile topological defects.
arxiv