Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Usage of Mobile X-Rays in Active Case-Finding for Tuberculosis
Indonesia has the world’s second-highest number of tuberculosis cases. More than 300,000 cases of tuberculosis in Indonesia have not been diagnosed or recorded, which are known as the missing cases. Undiagnosed tuberculosis patients will cause the spread
Cindra Paskaria +2 more
doaj +1 more source
An Error Analysis of Sentence Structure of Using Active and Passive Voice in Students’ Writing Composition (A Case Study toward the Second Year Students at SMA Pasundan 8 Bandung) Levina Firda Rasyid 137010033 [PDF]
This research tells about error analysis entitled An Error Analysis of Sentence Structure of Using Active and Passive Voicein Students’ Writing Composition (A Case Study toward the Second Year Students at SMA Pasundan 8 Bandung). The objective of this
Levina Firda Rasyid
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Background: Tuberculosis (TB) patients co-infected with human immunodeficiency virus (HIV) often lack the classic symptoms of pulmonary tuberculosis, making the diagnosis difficult. Current practices in resource-limited settings often indicate that these
Martha Alemayehu +8 more
doaj +1 more source
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Collaborative workshop: sustainable civil engineering proposals for real settings [PDF]
The objective is to familiarize students with real civil engineering problems as posed by social agents (e.g. a city council, a neighbourhood association, etc.) and to foster social responsibility, active and cooperative learning, teamwork and ...
Oller Ibars, Eva +2 more
core
Active Case Finding for Tuberculosis in the Community
Tuberculosis (TB) remains a major global health problem. The World Health Organization (WHO) has set ambitious targets to eliminate TB by 2035. To achieve this, dramatic reductions in TB incidence must be achieved worldwide. Strategies to achieve these targets include the early detection and treatment of all patients with TB, and preventative treatment
openaire +2 more sources
Community-wide active case finding and tuberculosis infection in children [PDF]
Guy B, Marks +2 more
openaire +2 more sources

