Results 41 to 50 of about 3,315 (309)
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Measurement + Control, 2019 In this paper, a hybrid fault tolerant control system is proposed for air–fuel ratio control of internal combustion gasoline engines based on Kalman filters and triple modular redundancy.
Arslan Ahmed Amin +1 more
doaj +1 more source
Fault Diagnosis and Fault-Tolerant Control Scheme for Quadcopter UAVs with a Total Loss of Actuator
Energies, 2019 Fault-tolerant control has drawn attention in recent years owning to its reliability and safe flight during missions. In this article, an active fault-tolerant control method is proposed to control a quadcopter in the presence of actuator faults and ...
Ngoc Phi Nguyen, Sung Kyung Hong
doaj +1 more source
Active Fault Tolerant Control of a Wind Farm System
IFAC-PapersOnLine, 2018 Abstract In order to enhance the ‘sustainability’ of offshore wind farms, thus skipping unplanned maintenance operations and costs, that can be important for offshore systems, the earlier management of faults represents the key point. Therefore, this work studies the development of an adaptive sustainable control scheme with application to a wind ...
S. Simani, C. Turhan
openaire +4 more sources
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Sliding-Mode-Based Current and Speed Sensors Fault Diagnosis for Five-Phase PMSM
Energies, 2021 The present paper deals with an active fault-tolerant speed tracking of a five-phase permanent magnet synchronous motor with currents and speed sensor failures.
Yemna Bensalem +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Ain Shams Engineering JournalThis paper presents an optimal fault-tolerant control (FTC) method for dynamic systems with distributed fault parameter uncertainty. According to the distributed characteristic of the fault parameter uncertainty domain and insufficient fault information,
Dan Du, Zetao Li
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source