Results 51 to 60 of about 2,554 (265)
Ain Shams Engineering JournalThis paper presents an optimal fault-tolerant control (FTC) method for dynamic systems with distributed fault parameter uncertainty. According to the distributed characteristic of the fault parameter uncertainty domain and insufficient fault information,
Dan Du, Zetao Li
doaj +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
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Energies, 2019 Due to the use of multiple observers and controllers in multi-sensor fault-tolerant control of PMSM drive systems, the algorithm is complex and the system control performance is affected.
Qinyue Zhu +4 more
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A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline
FEBS Open Bio, EarlyView.Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey +4 more
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Complexity, 2021 This paper presents an active fault-tolerant control strategy for quadrotor helicopters to simultaneously accommodate sensor faults and external disturbances.
Ban Wang, Peng Huang, Wei Zhang
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FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
Active Fault-Tolerant Cooperative Control for Multi-QUAVs Using Relative Measurement Information
DronesThis paper investigates actuator fault-tolerant cooperative control of multiple quadrotor unmanned aerial vehicles (multi-QUAVs) under restricted communication conditions, where only relative output measurements are available.
Yujiang Zhong +5 more
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FEBS Open Bio, EarlyView.Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta +7 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Active Fault Tolerant Control of MuPAL-a Using Sliding Modes [PDF]
2018 Annual American Control Conference (ACC), 2018 This paper proposes a simple adaptive sliding mode observer to estimate the effectiveness level of actuators and uses this information as part of an active fault tolerant controller. These observers create an FDI scheme at a ‘local’ level and the effectiveness estimates are used to drive the online control allocation component in the overall scheme ...
Lejun Chen +3 more
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