Results 51 to 60 of about 82,330 (304)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Sensor Fault Diagnosis and Fault Tolerant Control for Automated Guided Forklift
IEEE Access, 2021 For the problem of multiple sensor faults in the automated guided forklift (AGF), an equivalent model with system faults and disturbances is established. To detect multiple sensor faults in the AGF, a sliding mode observer (SMO) is proposed.
Hanguo Kang +6 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Measurement + Control, 2019 In this paper, a hybrid fault tolerant control system is proposed for air–fuel ratio control of internal combustion gasoline engines based on Kalman filters and triple modular redundancy.
Arslan Ahmed Amin +1 more
doaj +1 more source
Fault Diagnosis and Fault-Tolerant Control Scheme for Quadcopter UAVs with a Total Loss of Actuator
Energies, 2019 Fault-tolerant control has drawn attention in recent years owning to its reliability and safe flight during missions. In this article, an active fault-tolerant control method is proposed to control a quadcopter in the presence of actuator faults and ...
Ngoc Phi Nguyen, Sung Kyung Hong
doaj +1 more source
Sliding-Mode-Based Current and Speed Sensors Fault Diagnosis for Five-Phase PMSM
Energies, 2021 The present paper deals with an active fault-tolerant speed tracking of a five-phase permanent magnet synchronous motor with currents and speed sensor failures.
Yemna Bensalem +5 more
doaj +1 more source
Damage Tolerant Active Contro l: Concept and State of the Art [PDF]
, 2012 Damage tolerant active control is a new research area relating to fault tolerant control design applied to mechanical structures. It encompasses several techniques already used to design controllers and to detect and to diagnose faults, as well to ...
MECHBAL, Nazih, NOBREGA, Euripedes
core +2 more sources
Efficiency Improvement of Fault-Tolerant Three-Level Power Converters [PDF]
, 2018 Fault-tolerant power converters play a critical role in the transportation electrification. However, fault-tolerant operation, high efficiency, and low cost usually result in design criteria that have conflicting constraints and goals.
He, Jiangbiao +3 more
core +2 more sources
Active fault tolerant control of nonlinear systems: The cart-pole example [PDF]
International Journal of Applied Mathematics and Computer Science, 2011 Active fault tolerant control of nonlinear systems: The cart-pole exampleThis paper describes the design of fault diagnosis and active fault tolerant control schemes that can be developed for nonlinear systems. The methodology is based on a fault detection and diagnosis procedure relying on adaptive filters designed via the nonlinear geometric approach,
Marcello Bonfè +3 more
openaire +3 more sources
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source