Results 111 to 120 of about 4,733,293 (337)
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
地质科技通报Objective The Changle-Zhao'an fault zone is one of the primary active faults running along the coast of the Fujian Province. This fault zone has induced several destructive earthquakes and is thus a principal seismogenic structure in the Fujian Province.
Jisheng GUO +7 more
doaj +1 more source
Effect of active faults in the groundwater level of Shaharchay basin in Urmia [PDF]
تحقیقات کاربردی علوم جغرافیایی, 2017 حذف شدیک جمله Identify water resources management and proper application of relevant officials and managers are the main concern. Groundwater as a most important natural resources of Iran needs to planning and management of all aspects. In this regard, a
Tayebeh Kiani, Zahra Yousefi
doaj
Active Fault Localization of Actuators on Torpedo-Shaped Autonomous Underwater Vehicles. [PDF]
Sensors (Basel), 2021 Liu F +5 more
europepmc +1 more source
Potentially active faults in dam foundations [PDF]
, 1974 J. L. Sherard +2 more
openalex +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
地震科学进展The eastern margin of the Tibetan Plateau is composed of multiple secondary tectonic units which constitute typical “multi-level extrusion-rotation active tectonic system”.
Zhonghai Wu +4 more
doaj +1 more source
Design of active fault-tolerant control system for Air-fuel ratio control of internal combustion engines using fuzzy logic controller. [PDF]
Sci Prog, 2022 Riaz U, Amin AA, Tayyeb M.
europepmc +1 more source
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
Active faults and preliminary earthquake epicenters (1969-1970) in the southern part of the San Francisco Bay region [PDF]
, 1971 Robert D. Brown, W.H.K. Lee
openalex +1 more source