Results 131 to 140 of about 610,277 (358)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

New research progress on the strong earthquakes and seismogenic structures in eastern margin of Tibetan Plateau and adjacent areas: A preface for the special topic

地震科学进展
The eastern margin of the Tibetan Plateau is a tectonic transformation belt regulating the eastward extrusion of materials from the plateau. This area not only has high density active faults and high frequency strong earthquakes, but also has very ...
Zhonghai Wu, Zhongtai He, Ning Zhong, Jingxing Yu, Bo Zhang   +4 more
doaj   +1 more source

Study of Mechanical Response of Tunnels Crossing Active Faults in Different Burial Depths [PDF]

, 2023
Jiawei Zhang, Wanhua Zhao, Zhen Cui
openalex   +1 more source

Design of active fault-tolerant control system for Air-fuel ratio control of internal combustion engines using fuzzy logic controller. [PDF]

Sci Prog, 2022
Riaz U, Amin AA, Tayyeb M.
europepmc   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Fault2SHA Central Apennines database and structuring active fault data for seismic hazard assessment. [PDF]

Sci Data, 2021
Faure Walker J, Boncio P, Pace B, Roberts G, Benedetti L, Scotti O, Visini F, Peruzza L.   +7 more
europepmc   +1 more source

Estimation of Activity of the Active Fault.

Journal of Geography (Chigaku Zasshi), 1992
The nature of active faults is reviewed to estimate future activity. Criteria for the prediction of large earthquakes are given based on active faults and some earthquake-expectancy maps are shown.The activity of active faults is of a cyclic nature.
openaire   +2 more sources

Block Structure Bounded by Active Strike-slip Faults in the Northern Part of Kinki District, Southwest Japan [PDF]

, 1990
Geological and geophysical surveys were carried out to discover the hidden active faults and to estimate the dimensions of fractured zone in the northern part of Kinki district, southwest Japan.
Katsura, Ikuo
core  

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Deformation under a Young Volcanic Covered Area in Southern Garut, Indonesia: Insight from 3D Gravity Modelling

Journal of Mathematical and Fundamental Sciences
Destructive earthquakes are frequently related to inland active faults. In recent years, a significant number of shallow earthquakes with low magnitude have occurred in southern Garut, West Java, Indonesia.
Ilham Arisbaya, Edy Wijanarko, Prihadi Sumintadireja, Warsa Warsa, Hendra Grandis   +4 more
doaj   +1 more source