Results 91 to 100 of about 4,940,499 (251)
Local and Sustained Activity of Doxycycline Delivered with Layer-by-Layer Microcapsules
Biomacromolecules, 2016 Achieving localized delivery of small molecule drugs has the potential to increase efficacy and reduce off target and side effects associated with systemic distribution. Herein, we explore the potential use of layer-by-layer (LbL) assembled microcapsules for the delivery of doxycycline.
Luo, D, Gould, DJ, Sukhorukov, GB
openaire +4 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Active management of multiservice networks [PDF]
, 2000 Future multiservice networks will be extremely large and complex. Novel management solutions will be required to keep the management costs reasonable.
Marshall, I. W. +9 more
core +2 more sources
Covalent Layer-by-Layer Assembly of Redox-Active Polymer Multilayers
Langmuir, 2013 Poly(ferrocenyl(3-bromopropyl)methylsilane) and poly(ethylene imine) are employed in a layer-by-layer deposition process to form covalently connected, redox-active multilayer thin films by means of an amine alkylation reaction. The stepwise buildup of these multilayers on silicon, ITO, and quartz substrates was monitored by UV-vis absorption ...
Feng, Xueling +5 more
openaire +3 more sources
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Thermal state of permafrost in the high mountains of Mexico
Arctic, Antarctic, and Alpine ResearchThis article summarizes the thermal state of Mexican permafrost and its relationship to snow, ice, and geothermal environments. Ice-rich permafrost is observed near the summits of Citlaltépetl (Pico de Orizaba) and Iztaccíhuatl volcanoes. The lower limit
Kenji Yoshikawa +6 more
doaj +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Geosciences, 2019 Permafrost degradation caused by contemporary climate change significantly affects arctic regions. Active layer thickening combined with the thaw subsidence of ice-rich sediments leads to irreversible transformation of permafrost conditions and ...
Alexey Maslakov +4 more
doaj +1 more source
Layer-by-Layer Self-assembled Graphene Oxide Nanocontainers for Active Anticorrosion Application
, 2019 Layer-by-Layer Self-assembled Graphene Oxide Nanocontainers for Active Anticorrosion ...
Hou, Peimin +3 more
core +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source