Results 91 to 100 of about 5,429,053 (296)

Thermal state of permafrost in the high mountains of Mexico

Arctic, Antarctic, and Alpine Research
This article summarizes the thermal state of Mexican permafrost and its relationship to snow, ice, and geothermal environments. Ice-rich permafrost is observed near the summits of Citlaltépetl (Pico de Orizaba) and Iztaccíhuatl volcanoes. The lower limit
Kenji Yoshikawa, Victor Soto, Guillermo Ontiveros-Gonzales, Samael Oliver Vagamontes, Hugo Delgado Granados, Lorenzo Vazquez-Selem, David Palacios   +6 more
doaj   +1 more source

Covalent Layer-by-Layer Assembly of Redox-Active Polymer Multilayers

Langmuir, 2013
Poly(ferrocenyl(3-bromopropyl)methylsilane) and poly(ethylene imine) are employed in a layer-by-layer deposition process to form covalently connected, redox-active multilayer thin films by means of an amine alkylation reaction. The stepwise buildup of these multilayers on silicon, ITO, and quartz substrates was monitored by UV-vis absorption ...
Feng, Xueling, Cumurcu, Aysegul, Sui, Xiaofeng, Song, Jing, Hempenius, Mark A., Vancso, G. Julius   +5 more
openaire   +3 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Permafrost Degradation within Eastern Chukotka CALM Sites in the 21st Century Based on CMIP5 Climate Models

Geosciences, 2019
Permafrost degradation caused by contemporary climate change significantly affects arctic regions. Active layer thickening combined with the thaw subsidence of ice-rich sediments leads to irreversible transformation of permafrost conditions and ...
Alexey Maslakov, Natalia Shabanova, Dmitry Zamolodchikov, Vasili Volobuev, Gleb Kraev   +4 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Tracer Velocity Versus Bedload Velocity: Derivation of the Unsteady Virtual Bedload Velocity From Decelerating Tracers

Water Resources Research
During rest periods, bedload tracers can be buried, while transport can move them to locations with different bed shear stresses or a different riverbed composition. This affects the mobility of the tracers compared to that of the bedload at the location
M. Klösch, S. Pessenlehner, P. Gmeiner, H. Habersack   +3 more
doaj   +1 more source

Active Control of Ionized Boundary Layers [PDF]

International Journal of Bifurcation and Chaos, 1998
The challenging problems, in the field of control of chaos or of transition to chaos, lie in the domain of infinite-dimensional systems. Access to all variables being impossible in this case and the controlling action being limited to a few collective variables, it will not in general be possible to drive the whole system to the desired behavior.
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source