Results 101 to 110 of about 82,572 (267)

Active layer thickness observations

, 2022
Dataset of  active layer thickness  (ALT) observations on the Qinghai Plateau. 
Yixin Xu (12581685), Tao Zhou (12581585), Peixin Yu (14039823), Jingyu Zeng (12581056), Jingzhou Zhang (14039825), Yajie Zhang (14039819), Hui Luo (14039822), XIA LIU (14038194)   +7 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Stereo Digital Particle Image Velocimetry Investigation of a Free Surface Mixing Layer [PDF]

, 2005
Shear flows in the vicinity of a free surface are a problem with numerous applications, perhaps the most obvious being the wakes of seagoing surface vessels.
Dooley, Bradley Scott
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Thermal state of permafrost in the high mountains of Mexico

Arctic, Antarctic, and Alpine Research
This article summarizes the thermal state of Mexican permafrost and its relationship to snow, ice, and geothermal environments. Ice-rich permafrost is observed near the summits of Citlaltépetl (Pico de Orizaba) and Iztaccíhuatl volcanoes. The lower limit
Kenji Yoshikawa, Victor Soto, Guillermo Ontiveros-Gonzales, Samael Oliver Vagamontes, Hugo Delgado Granados, Lorenzo Vazquez-Selem, David Palacios   +6 more
doaj   +1 more source

Permafrost Degradation within Eastern Chukotka CALM Sites in the 21st Century Based on CMIP5 Climate Models

Geosciences, 2019
Permafrost degradation caused by contemporary climate change significantly affects arctic regions. Active layer thickening combined with the thaw subsidence of ice-rich sediments leads to irreversible transformation of permafrost conditions and ...
Alexey Maslakov, Natalia Shabanova, Dmitry Zamolodchikov, Vasili Volobuev, Gleb Kraev   +4 more
doaj   +1 more source

Numerical simulation of boundary-layer control using MEMS actuation [PDF]

MEMS actuators and their effect on boundary layers is investigated using numerical simulation. The thesis is specifically focussed on jet actuators and their application to the targeted control of turbulent boundary layers.
Lockerby, Duncan A.
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Control of shock-induced boundary layer separation at supersonic speeds

, 2007
PhDThe results of a systematic experimental investigation into the effects that Sub- Boundary Layer Vortex Generators (SBVGs) have on reducing normal shock-induced turbulent boundary layer separation are presented.
Cohen, Giel S, Cohen, Giel S.
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source