Results 81 to 90 of about 5,429,053 (296)

Permafrost Table Temperature (2008–2021) in Deception Island, Antarctica

Geoscience Data Journal
This manuscript presents a comprehensive presentation of ground temperature data collected at 16 nodes of the 121 of the Crater Lake Circumpolar Active Layer Monitoring (CALM) site on Deception Island, Antarctica, from 2008 to early 2022. Each one of the
M. A. dePablo, M. Ramos
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

On inferring isoprene emission surface flux from atmospheric boundary layer concentration measurements [PDF]

, 2009
We examine the dependence of the inferred isoprene surface emission flux from atmospheric concentration on the diurnal variability of the convective boundary layer (CBL).
K. van den Dries, J. Vilà-Guerau de Arellano, Dries, K., van den, Pino, D., Vilà-Guerau de Arellano, J., van den Dries, K., D. Pino   +6 more
core   +2 more sources

Application Layer Active Networks. [PDF]

, 1998
Marshall, Ian W.
core   +4 more sources

Linear disturbances on discontinuous permafrost: implications for thaw-induced changes to land cover and drainage patterns

Environmental Research Letters, 2013
Within the zone of discontinuous permafrost, linear disturbances such as winter roads and seismic lines severely alter the hydrology, ecology, and ground thermal regime.
Tyler J Williams, William L Quinton, Jennifer L Baltzer   +2 more
doaj   +1 more source

Local and Sustained Activity of Doxycycline Delivered with Layer-by-Layer Microcapsules

Biomacromolecules, 2016
Achieving localized delivery of small molecule drugs has the potential to increase efficacy and reduce off target and side effects associated with systemic distribution. Herein, we explore the potential use of layer-by-layer (LbL) assembled microcapsules for the delivery of doxycycline.
Luo, D, Gould, DJ, Sukhorukov, GB
openaire   +4 more sources

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Transportation Development Division, Active Transportation Section, March 1, 2013 [PDF]

, 2013
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF caption (viewed on April 11, 2014)Mode of ...

core  

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source