Results 101 to 110 of about 2,207,935 (300)

Electron drag in ferromagnetic structures separated by an insulating interface

, 2018
We consider electron drag in a system of two ferromagnetic layers separated by an insulating interface. The source of it is expected to be magnon-electron interactions.
Galperin, Y. M., Kozub, V. I., Muradov, M. I.   +2 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Permafrost Degradation within Eastern Chukotka CALM Sites in the 21st Century Based on CMIP5 Climate Models

Geosciences, 2019
Permafrost degradation caused by contemporary climate change significantly affects arctic regions. Active layer thickening combined with the thaw subsidence of ice-rich sediments leads to irreversible transformation of permafrost conditions and ...
Alexey Maslakov, Natalia Shabanova, Dmitry Zamolodchikov, Vasili Volobuev, Gleb Kraev   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Thermal state of permafrost in the high mountains of Mexico

Arctic, Antarctic, and Alpine Research
This article summarizes the thermal state of Mexican permafrost and its relationship to snow, ice, and geothermal environments. Ice-rich permafrost is observed near the summits of Citlaltépetl (Pico de Orizaba) and Iztaccíhuatl volcanoes. The lower limit
Kenji Yoshikawa, Victor Soto, Guillermo Ontiveros-Gonzales, Samael Oliver Vagamontes, Hugo Delgado Granados, Lorenzo Vazquez-Selem, David Palacios   +6 more
doaj   +1 more source

Kinetics of Ion Transport in Perovskite Active Layers and Its Implications for Active Layer Stability

Journal of the American Chemical Society, 2015
Solar cells fabricated using alkyl ammonium metal halides as light absorbers have the right combination of high power conversion efficiency and ease of fabrication to realize inexpensive but efficient thin film solar cells. However, they degrade under prolonged exposure to sunlight. Herein, we show that this degradation is quasi-reversible, and that it
Monojit, Bag, Lawrence A, Renna, Ramesh Y, Adhikari, Supravat, Karak, Feng, Liu, Paul M, Lahti, Thomas P, Russell, Mark T, Tuominen, D, Venkataraman   +8 more
openaire   +3 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Contact Topology and the Structure and Dynamics of Cholesterics

, 2017
Using tools and concepts from contact topology we show that non-vanishing twist implies conservation of the layer structure in cholesteric liquid crystals.
Machon, Thomas
core   +1 more source