Results 151 to 160 of about 6,656,778 (331)
Anisotropic swim stress in active matter with nematic order [PDF]
, 2018 Wen Yan, John F Brady
openalex +1 more source
Active Matter that Mimics Turbulence in Space and Time [PDF]
, 2020 Erika K. Carlson
openalex +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Synchronization in collectively moving inanimate and living active matter. [PDF]
Nat Commun, 2023 Riedl M +4 more
europepmc +1 more source
Broken Machines or Active Bodies? Part 1. Ways of Talking About Health and Why It Matters
, 2023 Samantha Bunzli +9 more
openalex +2 more sources
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Publisher Correction: Active matter in space. [PDF]
NPJ Microgravity, 2023 Volpe G +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Emergence of precursor instabilities in geo-processes: Insights from dense active matter. [PDF]
Heliyon, 2023 Regenauer-Lieb K, Hu M.
europepmc +1 more source