Results 111 to 120 of about 3,741,697 (242)

Safety of Prescription Nonsteroidal Anti‐inflammatory Drugs in Adults With Inflammatory Bowel Disease: Data From a Large Administrative Claims Cohort

open access: yesArthritis Care &Research, EarlyView.
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer   +4 more
wiley   +1 more source

Cell culture media: An active pharmaceutical ingredient or ancillary material?

open access: yes, 2018
Cell culture media are used to manufacture cell-based therapies. A number of essential materials are involved in the manufacture of cellbased therapies, including the active pharmaceutical ingredient (API), ancillary materials (AMs), and raw materials ...
Alturkistani, A   +3 more
core  

Crystallization of active pharmaceutical ingredient on substrates

open access: yes, 2014
Due to the demand of individualized pharmaceutical formulation, the application of drop printing (DP) technology on manufacturing of pharmaceutical devices has received extensive attention.
Hsu, Hsin-Yun
core   +1 more source

Perceived Impacts and Predictors of Cannabis Products Used by Patients with Rheumatologic Conditions in Alberta, Canada: A Multivariable Analysis of Cross‐Sectional Survey Data

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among patients with rheumatologic conditions and their associations with patient factors, patient‐reported perceived side effects, and positive impacts.
Susan Zhang   +10 more
wiley   +1 more source

Quality by design optimisation of active pharmaceutical ingredient dispersions based on physicochemical parameters [PDF]

open access: yes, 2014
Current information lacks richness in systematic methods that may give an indication as to the effectiveness of a specific set of dispersing conditions prior to their application, particularly for dispersions in hydrophobic media.
Farrugia, Claude   +3 more
core  

Real‐World Safety and Effectiveness of JAK Inhibitors in Systemic Sclerosis: A Propensity‐Matched Study From the EUSTAR Cohort

open access: yesArthritis Care &Research, EarlyView.
Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato   +27 more
wiley   +1 more source

Cleaning Validation of a Multipurpose Plant for Active Pharmaceutical Ingredient Bulk Production

open access: yesCHIMIA, 2000
One of the key issues in the manufacture of active pharmaceuticals ingredients in multipurpose non-dedicated equipment is to adequately address the potential for cross-contamination.
Mirko Moser   +2 more
doaj  

Efficient Screening of Coformers for Active Pharmaceutical Ingredient Cocrystallization. [PDF]

open access: yesCryst Growth Des, 2022
Sugden IJ   +4 more
europepmc   +1 more source

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