Results 101 to 110 of about 3,921,277 (285)
Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong +10 more
wiley +1 more source
An improved procedure for synthesis of lenalidomide as an active pharmaceutical ingredient
Results in ChemistryLenalidomide is a second-generation immunomodulatory drug widely used in the treatment of multiple myeloma and myelodysplastic syndromes. Market studies indicate that the demand for lenalidomide rising steadily due to the increasing prevalence of ...
Elaheh Ataollahi +3 more
doaj +1 more source
FAST AND SUSTAINABLE ACTIVE PHARMACEUTICAL INGREDIENT (API) SCREENING IN OVER-THE-COUNTER AND PRESCRIPTION DRUG PRODUCTS BY SURFACE-ASSISTED PLASMA-BASED DESORPTION/IONIZATION HIGH-RESOLUTION MASS SPECTROMETRY Fast and Sustainable Active Pharmaceutical ...
Heide, Maximilian +3 more
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Vascular Disease, Non‐Steroidal Anti‐Inflammatory Drugs and Risk of Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives A history of vascular disease has been shown to be associated with an increased risk of Parkinson's disease, but this may be due to reverse causation. In addition, non‐steroidal anti‐inflammatory drugs are thought to reduce Parkinson's disease risk, but evidence is inconsistent and confounding by prior vascular disease is possible ...
Clare Wotton +4 more
wiley +1 more source
Raman Spectroscopy for the Quantitative Analysis of Solid Dosage Forms of the Active Pharmaceutical Ingredient of Febuxostat. [PDF]
ACS Omega, 2023 Rimsha G +11 more
europepmc +1 more source
Cell culture media: An active pharmaceutical ingredient or ancillary material?
, 2018 Cell culture media are used to manufacture cell-based therapies. A number of essential materials are involved in the manufacture of cellbased therapies, including the active pharmaceutical ingredient (API), ancillary materials (AMs), and raw materials ...
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Choroid plexus volume (CPV) has been proposed as a neuro‐immunological marker of multiple sclerosis (MS), but its relevance in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD) remains uncertain. We analyzed CPV in 43 individuals with MOGAD, 48 with MS, and 44 healthy controls using a Bayesian Gaussian mixture modeling ...
Jae‐Won Hyun +4 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno +19 more
wiley +1 more source
High-pressure studies in the supercooled and glassy state of the strongly associated active pharmaceutical ingredient-ticagrelor. [PDF]
Sci Rep, 2023 Jesionek P +4 more
europepmc +1 more source
, 2006 The invention provides methods for the adsorption of an active pharmaceutical ingredient on titianium dioxide nanoparticles which can be orally ingested allowing the drug release into the intestine without causing side effects to the upper ...
DISSETTE, Valeria +5 more
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