Results 121 to 130 of about 3,921,277 (285)

Subjective Cognitive Concerns and Cognitive Trajectories in Parkinson's Disease: Biomarker Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the relationship of subjective cognitive concerns (SCC) with biomarkers of Alzheimer's disease (AD), neurodegeneration, and Parkinson's disease (PD) and domain‐specific cognitive trajectories among cognitively unimpaired persons with de novo PD. Method Cognitively unimpaired participants with SCC (n = 294) and without SCC (
Francesca V. Lopez, Fareshte Erani, Katherine J. Bangen, David G. Coughlin, Douglas Galasko, Kelsey R. Thomas   +5 more
wiley   +1 more source

Cleaning Validation of a Multipurpose Plant for Active Pharmaceutical Ingredient Bulk Production

CHIMIA, 2000
One of the key issues in the manufacture of active pharmaceuticals ingredients in multipurpose non-dedicated equipment is to adequately address the potential for cross-contamination.
Mirko Moser, Giorgio Calderari, Paolo Morini   +2 more
doaj  

Efficient Screening of Coformers for Active Pharmaceutical Ingredient Cocrystallization. [PDF]

Cryst Growth Des, 2022
Sugden IJ, Braun DE, Bowskill DH, Adjiman CS, Pantelides CC.   +4 more
europepmc   +1 more source

Novel Pharmaceutical Compositions Comprising Levetiracetam

, 2011
The present invention relates to a pharmaceutical composition comprising levetiracetam as active ingredient, the invention relates specifically to a prolonged release formulation.info:eu-repo/semantics ...
Deleers, Michel, Goffin, C, Fanara, Domenico, Berwaer, M, Boonen, Michaël   +4 more
core  

Neural network classification of pharmaceutical active ingredient from near infrared spectra

, 2015
This paper presents results from a scoping study undertaken with the intention of demonstrating the applicability of reflectance Near-Infrared (NIR) spectroscopy in classification of pharmaceutical type based on active ingredient. The part of the process
Ashley Yan, Yan, Ashley, Nigel Yee, Yee, Nigel   +3 more
core   +1 more source

Systemic Extracerebral Atherosclerotic Burden and Dementia Risk After Incident Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Stroke survivors are at increased risk of dementia, but clinically accessible markers of risk heterogeneity remain limited. Previous studies have largely examined atherosclerotic disease in individual vascular beds rather than the overall burden of systemic extracerebral atherosclerosis.
Zhexuan Yu, Tianxue Chen, Wei Jin, Weifeng Jin, Haitong Wan   +4 more
wiley   +1 more source

Investigation of Complement Activation and Cytokine Signatures in AQP4+ NMOSD, MOGAD, and MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Aquaporin‐4‐IgG seropositive neuromyelitis optica spectrum disorder (AQP4+ NMOSD), myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD), and multiple sclerosis (MS) are pathophysiologically distinct neuroinflammatory disorders. Complement activation is a major mechanism of injury in AQP4+ NMOSD, whereas its role in
Angeliki G. Filippatou, Susana Dominguez‐Penuela, David Acero‐Garces, Georgios Gakis, Matthew D. Smith, Yasmin Resto, Maria Reyes‐Mantilla, Haiwen Chen, Isabella Hernandez, Yana Said, Andrea Salazar‐Camelo, Christina Huynh, Alessia Tassoni, Ted Yednock, Rick Artis, Yaisa Andrews‐Zwilling, Scott D. Newsome, Shiv Saidha, Pavan Bhargava, Ellen M. Mowry, Kathryn C. Fitzgerald, Peter A. Calabresi, Carlos A. Pardo, Elias S. Sotirchos   +23 more
wiley   +1 more source

Enantioselective Organophotocatalytic Telescoped Synthesis of a Chiral Privileged Active Pharmaceutical Ingredient. [PDF]

Chemistry, 2022
Herbrik F, Sanz M, Puglisi A, Rossi S, Benaglia M.   +4 more
europepmc   +1 more source

Dysregulated Cholesterol Metabolism, Chronic Inflammation, and Disability in Severe Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Dysregulated lipid metabolism, which can affect remyelination and neural repair, has not been extensively investigated in progressive multiple sclerosis (PMS). The goal was to examine whether dysregulated cholesterol metabolism was associated with disability in PMS. Methods The study sample comprised 53 Severe PMS patients (Expanded
Taylor R. Wicks, Mujeeb Shittu, Anna Wolska, Diala Ghazal, Bianca Weinstock‐Guttman, Alexander Burnham, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +8 more
wiley   +1 more source

Active pharmaceutical ingredient (API) chemicals: a critical review of current biotechnological approaches. [PDF]

Bioengineered, 2022
Kumar V, Bansal V, Madhavan A, Kumar M, Sindhu R, Awasthi MK, Binod P, Saran S.   +7 more
europepmc   +1 more source