Analysis of complex drugs by comprehensive two-dimensional gas chromatography and high-resolution mass spectrometry: detailed chemical description of the active pharmaceutical ingredient sodium bituminosulfonate and its process intermediates. [PDF]
Schwalb L +6 more
europepmc +1 more source
Trinuclear iron oxo‐bridged catalytic ensembles stabilized by aspartic‐acid‐derived carbon dots provide an effective platform for alkaline oxygen evolution. Mixed‐valence charge balancing, inner‐sphere charge transport, and work‐function alignment within the N/O‐rich carbon framework promote cooperative Fe‐site chemistry and efficient OER ...
Megha A. Deshmukh +13 more
wiley +1 more source
Is price associated with the quality of medicines? Evidence from active pharmaceutical ingredient testing in Nigeria. [PDF]
Montás MC, Anyakora C, Maffioli EM.
europepmc +1 more source
Dissolution Kinetics of a BCS Class II Active Pharmaceutical Ingredient: Diffusion-Based Model Validation and Prediction. [PDF]
Gao Y, Glennon B, He Y, Donnellan P.
europepmc +1 more source
A pharmaceutical tablet capable of releasing the active ingredients contained therein at subsequent times produced via the steps of: a) preparing a tablet consisting of three superposed layers, the upper layer containing an active ingredient, the ...
La Manna Aldo +2 more
core
A dynamic interfacial semi‐interpenetrating polymer network is constructed by sequential assembly of β‐sheet‐rich SF and CS‐RL. The SF framework provides mechanical strength, while dynamically associated CS‐RL enables local rearrangement, allowing droplets to rapidly reconfigure without loss of interfacial integrity.
Yaping Zhang +7 more
wiley +1 more source
Stereoselective Bio-Organocatalytic Cascade to Chiral Amides as Active Pharmaceutical Ingredient Intermediates Using ω-Transaminase and Choline Chloride Under Microwave Irradiation. [PDF]
Romano S +7 more
europepmc +1 more source
Development of a rapid GC-FID method to simultaneously determine triethylamine, diisopropylamine, and 1,1,3,3-tetramethylguanidine residues in an active pharmaceutical ingredient. [PDF]
Shou M, Qiu H.
europepmc +1 more source
A pharmaceutical tablet capable of releasing the active ingredients contained therein at subsequent times produced via the steps of: a) preparing a tablet consisting of three superposed layers, the upper layer containing an active ingredient, the ...
La Manna Aldo +2 more
core
Endosomal Escape of siRNA Polyplexes: A Molecular Dynamics Perspective on Underlying Mechanisms
Molecular dynamics simulations reveal distinct endosomal escape mechanisms of siRNA nanoparticles, ranging from electrostatic membrane attachment to hydrophobic membrane fusion. Hydrophobic residues and anionic endosomal lipids emerge as key determinants of membrane disruption, linking molecular interactions to experimental delivery performance and ...
Katharina M. Steinegger +5 more
wiley +1 more source

