Results 171 to 180 of about 3,741,697 (242)

Development and validation of a method for N-(4-methoxy-2-nitrophenyl) acetamide contamination in active pharmaceutical ingredient

Aktivna farmaceutska tvar (engl. Active Pharmaceutical Ingredient, API) predstavlja osnovni nositelj farmakološkog djelovanja lijeka te, u kombinaciji s pomoćnim tvarima, čini gotov farmaceutski proizvod. Za osiguranje učinkovitosti i sigurnosti primjene
Grahek, Petra
core  

Hydrogels Augmented With Artificial Sweeteners can Inhibit Multidrug‐Resistant Acinetobacter baumannii Growth and Biofilm Formation While Demonstrating Safety in Pre‐Clinical Pilot Human Trials

Advanced Healthcare Materials, EarlyView.
Using PVA–borax hydrogels as carriers for off‐the‐shelf artificial sweeteners to fight multidrug‐resistant A. baumannii. These soft, biocompatible hydrogels rapidly reduce bacterial viability within multidrug‐resistant A. baumannii biofilms by more than 99% within one hour and sustain antimicrobial activity over time, while demonstrating safety in both
Jie Han, Mohamed Soliman, Bin Zhang, Dominika Krawiel, Ronan R. McCarthy   +4 more
wiley   +1 more source

Computational Methods for Modeling Lipid-Mediated Active Pharmaceutical Ingredient Delivery. [PDF]

Mol Pharm
Paloncýová M, Valério M, Dos Santos RN, Kührová P, Šrejber M, Čechová P, Dobchev DA, Balsubramani A, Banáš P, Agarwal V, Souza PCT, Otyepka M.   +11 more
europepmc   +1 more source

Patient‐Derived 3D Heart‐On‐a‐Chip Model of Dilated Cardiomyopathy With Embedded Bead‐Based Mapping of Tissue Contractility

Advanced Healthcare Materials, EarlyView.
A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi, Ludovic Mouttet, Shihao Cui, Yasaman Hekmatnia, Mehran Mottahedi, Ida Derish, Naimeh Rafatian, Mark Aurousseau, Gregor Andelfinger, Renzo Cecere, Houman Savoji   +10 more
wiley   +1 more source

Development of quantitative analysis method of active pharmaceutical ingredient in Ciklodol tablets

, 2014
Ciklodola tablešu aktīvās farmaceitiskās vielas kvantitatīvā satura noteikšanas metodes izstrāde. Stapkēvičs S., darba vadītāji mag. ķīm. K. Kuprevičs un prof. A. Vīksna. Maģistra darbs, 47 lappuses, 13 attēli, 15 tabulas, 33 literatūras avoti.
Stapkēvičs, Sandis
core  

Determination of an Anti-Parasitic Active Pharmaceutical Ingredient in Wastewater Effluents Using Capillary Zone Electrophoresis. [PDF]

Electrophoresis
O'Sullivan-Carroll E, Hogan A, O'Mahoney N, Howlett S, Pyne C, Downing P, Lynch M, Moore E.   +7 more
europepmc   +1 more source

Engineering Concentration‐Dependent Intravitreal Mobility via Cyclic Arginine‐Enriched Nanocarrier Surface Modification: In Vivo Proof‐of‐Concept in a Porcine Large Animal Model

Advanced Healthcare Materials, EarlyView.
In this study, Hammer et al. highlight cyclic‐arginine surface engineering as a highly biocompatible, controllable, and concentration‐dependent regulator of intravitreal nanoparticle mobility in vivo in a translational large animal model. The cyclic arginine surface‐modification supports the development of next‐generation biomaterials for long‐acting ...
Maximilian Hammer, Bryan Calder Ackermann, Anna Stoß, Niklas Junker, Ludwig Geisweid, Sabrina Wohlfart, Jonathan Herth, Simon William Pohl, Manuel Ben Böhmann, André Schulz, Victor Aristide Augustin, Gerd Uwe Auffarth, Philipp Uhl   +12 more
wiley   +1 more source

Matrinium-based active pharmaceutical ingredient ionic liquids: chain length effect on micellization, bioactivity and thermodynamic behaviors. [PDF]

RSC Adv
Yan Z, Xu M, Lu H.
europepmc   +1 more source

2‐Deoxyglucose Dendrimer‐Enabled Niclosamide Delivery to FRβ‐Expressing Macrophages Alleviates Endometriosis Progression and Associated Hyperalgesia

Advanced Healthcare Materials, EarlyView.
A folic acid (FA)‐conjugated 2‐deoxyglucose dendrimer selectively targets FRβ+ macrophages in endometriotic lesions, enabling precise intracellular delivery of niclosamide. This nonhormonal nanomedicine enhances drug solubility, provides controlled intracellular release, suppresses lesion growth, reduces inflammation and pain, and establishes FRβ ...
Anubhav Dhull, Mingxin Shi, Madeleine E. Harvey, Taylor M. Page, Rishi Sharma, Kenneth John Goody, Aqib Iqbal Dar, Nash S. Moawad, Vijay Kumar Sirohi, Paul S. Cooke, Kanako Hayashi, Anjali Sharma   +11 more
wiley   +1 more source

Full-active pharmaceutical ingredient nanosensitizer for augmented photoimmunotherapy by synergistic mitochondria targeting and immunogenic death inducing. [PDF]

MedComm (2020)
Li X, Wang H, Li Z, Liu S, Chen Y, Ruan Z, Yao Z, Wei G, Cao C, Zheng W, Guan W.   +10 more
europepmc   +1 more source