Results 111 to 120 of about 4,119,069 (249)

Artificial Intelligence–Driven and Digital Practices for Circular Business and Finance: Insights for Advancing Hubs for Circularity

Business Strategy and the Environment, EarlyView.
ABSTRACT The emerging concept of Hubs for Circularity (H4Cs) presents an opportunity to create collaborative, self‐sustaining regional industrial ecosystems that drive circular economy transitions at scale. However, the operationalisation of H4Cs faces financial, organisational and data‐driven challenges.
Aditya Tripathi, Marcos R. Machado, Laura Spierdijk, Devrim Murat Yazan   +3 more
wiley   +1 more source

From Managing Innovation to Governing Value: Reconceptualizing the Role of Intellectual Property in the Sustainable Business Model

Business Strategy and the Environment, EarlyView.
ABSTRACT The role of intellectual property (IP) in promoting or hindering sustainable innovation now forms a topical issue in innovation management. Its role in the sustainable business model remains imperfectly understood however, creating a simplified view of IP in relation to corporate sustainable development. Hence, this study sought to examine how
Sarah van Santen
wiley   +1 more source

Trends and Future Directions in Organic Chemistry for Drug Discovery

Chemistry – A European Journal, EarlyView.
Organic synthesis is being reshaped by the convergence of catalytic innovation, automation, artificial intelligence, and emerging therapeutic modalities. Late‐stage functionalization, photoredox and electrochemical methods, biocatalysis, flow chemistry, DELs, and proximity‐based drugs are examined as components of closed‐loop discovery.
Paweł Kozyra, Maciej Masłyk
wiley   +1 more source

Thermodynamic sensitivity and transferability limitations of Pharma Mod UNIFAC for aqueous solubility prediction of sulfonamide APIs

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract Predicting the aqueous solubility of active pharmaceutical ingredients (APIs) remains challenging because highly dilute systems are particularly sensitive to activity‐coefficient calculations and solid‐reference thermodynamic properties. In this work, we evaluated Pharma Mod UNIFAC for predicting the aqueous solubility of sulfonamide‐based ...
Geovanny E. Pan‐Echeverría, José Fernando Barragán‐Aroche, María de Lourdes Mayet‐Cruz, Helgi Jung‐Cook   +3 more
wiley   +1 more source

Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access

Clinical Pharmacology &Therapeutics, EarlyView.
Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian, Moherndran Archary, Daniel B. Hawcutt, Rachel Daley, Edmund Capparelli, Adeniyi Olagunju   +5 more
wiley   +1 more source

Redox Biocatalysis in Lidocaine‐Based Hydrophobic Deep Eutectic Solvents: Non‐Conventional Media Outperform Aqueous Conditions

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
Two hydrophobic DESs, lidocaine/oleic acid and lidocaine/decanoic acid, were utilized as reaction media that were enzyme‐compatible and highly substrate‐solubilizer for carbonyl reduction catalyzed by horse liver alcohol dehydrogenase, focusing on the effect of water contents and on maximizing substrate loadings, which showcases for the first time the ...
Ningning Zhang, Viktoria Lahmann, Jan Philipp Bittner, Pablo Domínguez de María, Sven Jakobtorweihen, Irina Smirnova, Selin Kara   +6 more
wiley   +1 more source

Impact of Drone Versus Car Transport on Anti‐Doping Sample Integrity Over Short Distances: A Proof‐Of‐Concept Study

Drug Testing and Analysis, EarlyView.
This proof‐of‐concept study evaluated the impact of short‐distance drone transport on anti‐doping sample integrity compared with traditional car transport. Targeted assays and untargeted metabolomics revealed equivalent biological profiles between methods, confirming that drone delivery preserves sample integrity for the athlete biological passport ...
I. Al‐Mohannadi, M. Y. Al‐Jaber, M. Al‐Nesf, W. Samsam, Abdulaziz Farooq, N. M. Thomas, M. Stuart, N. Robinson, G. Zangenfeind, D. Rovira, N. Mohamed‐Ali, A. Beotra, V. Mohamed‐Ali, M. Al‐Maadheed   +13 more
wiley   +1 more source

Effects of flow‐controlled expiration on oxygenation and early recovery in horses undergoing general anaesthesia

Equine Veterinary Journal, EarlyView.
Abstract Background FLow‐controlled EXpiration (FLEX) has been shown to significantly enhance oxygenation in horses under clinical and experimental conditions. Objectives To compare pulmonary gas exchange during early recovery following general anaesthesia in horses ventilated with FLEX compared with conventional intermittent positive pressure ...
Allison Mika, Jerrianne Brandly, Alycia Frampton, Hope Douglas, Miranda Starr, Henry Benchimol, Klaus Hopster   +6 more
wiley   +1 more source

Chemical structures of the 14 active pharmaceutical ingredients (API) of rhubarb.

, 2016
Chemical structures of the 14 active pharmaceutical ingredients (API) of rhubarb.
Huijuan Hu (227646), Shengli Wei (2637028), Guangxi Ren (2637031), Chunsheng Liu (496714), Yanpeng Li (125043), Li Li (14993)   +5 more
core   +1 more source

Warmed intravenous fluid administration attenuated a reduction in body temperature in anaesthetised horses

Equine Veterinary Journal, EarlyView.
Abstract Background Peri‐anaesthetic hypothermia is a well‐documented complication of general anaesthesia and is associated with prolonged recovery, impaired wound healing, and delayed coagulation. Fluid warmers can be used to mitigate heat loss, but there is little evidence supporting their effectiveness in equine anaesthesia.
Miranda P. Starr, Alycia Frampton, Allison Mika, Klaus Hopster, Hope Douglas   +4 more
wiley   +1 more source