Results 91 to 100 of about 4,119,069 (249)
Ibuprofen-Amino Acids Co-Crystal Screening Via Co-Grinding Methods
MATEC Web of Conferences, 2016 The importance of pharmaceutical co-crystals now has been recognized in order to improve the research and development in pharmaceutical industries. Low solubility of active pharmaceutical ingredient (API) has led to the growth of new pharmaceutical co ...
Othman Muhamad Fitri +4 more
doaj +1 more source
Exploratory Study on Active Pharmaceutical Ingredient Manufacturing for Essential Medicines
, 2009 Active Pharmaceutical Ingredients (API) of good quality is core to the manufacturing of effective and safe essential drugs. The price of APIs is the main cost driver for manufacturing. Only a limited number of large
Betsch, Ekkehard, Bumpas, Janet
core +1 more source
Multimodal Learning with Rashomon Analysis for Battery Discharge Capacity Prediction
Advanced Intelligent Discovery, EarlyView.Multimodal fusion integrates composition, crystal‐structure, and radial‐distribution descriptors to predict battery discharge capacity. Rashomon analysis across near‐optimal models reveals that explanatory variation is structured rather than arbitrary, separating stable mechanistic signals from model‐contingent attributions and providing a more ...
Jue Gong +4 more
wiley +1 more source
A Generative AI Framework to Predict Cardiomyocyte Contraction Function From Single Static Images
Advanced Intelligent Discovery, EarlyView.A single static hiPSC‐cardiomyocyte image is fed into a U‐Net‐GAN framework, which directly predicts a pixel‐resolved contraction heatmap without time‐lapse imaging. StyleGAN2‐generated synthetic cell–heatmap pairs augment training, improving prediction fidelity (SSIM = 0.84).
Andrew Kowalczewski +5 more
wiley +1 more source
Co-Crystal Screening of Diclofenac
Pharmaceutics, 2011 In the pharmaceutical industry, co-crystals are becoming increasingly valuable as crystalline solids that can offer altered/improved physical properties of an active pharmaceutical ingredient (API) without changing its chemical identity or biological ...
John Desper +2 more
doaj +1 more source
Cell culture media: An active pharmaceutical ingredient or ancillary material?
, 2018 Cell culture media are used to manufacture cell-based therapies. A number of essential materials are involved in the manufacture of cellbased therapies, including the active pharmaceutical ingredient (API), ancillary materials (AMs), and raw materials ...
core
Angewandte Chemie International Edition, EarlyView.We introduce the Aza‐Büchner–Curtius–Schlotterbeck (ABCS) reaction: A mild, catalyst‐free method for homologating aryl imines. Diverging from the traditional BCS mechanism, the diazo intermediate undergoes selective C─C insertion to form an all‐carbon quaternary center.
Simon O. Angerer +6 more
wiley +1 more source
, 2012 A systematic framework is proposed for the design of continuous pharmaceutical manufacturing processes. Specifically, the design framework focuses on organic chemistry based, active pharmaceutical ingredient (API) synthetic processes, but could ...
Kiil, Søren +5 more
core +1 more source
Journal of the Association for Information Science and Technology, EarlyView.Abstract Context‐centric proactive information delivery (PID) is a relatively underexplored domain within recommender systems (RS) aimed at enhancing Knowledge Workers' productivity by proactively providing relevant information during digital tasks.
Mahta Bakhshizadeh +4 more
wiley +1 more source
Pharmaceutical formulation with improved solubility and bioavailability
, 2018 The present invention relates to a pharmaceutical formulation comprising at least one active pharmaceutical ingredient (API) having low aqueous solubility or a pharmaceutically acceptable salt thereof in the form of particles of a size between 1 and 800 ...
Lagarón Cabello, José María +4 more
core +1 more source