Results 71 to 80 of about 7,041 (257)
International Journal of Chemical Reactor Engineering, 2010 Solubility, which defines the liquid /solid equilibrium, is a key parameter to control a crystallization process. This work is focused on the effects of pH, temperature and impurities on the aqueous solubility of an Active Pharmaceutical Ingredient (API).As the API is a weak acid (pKa = 3.7), its solubility increases with the pH.
Estime, Nicolas +3 more
openaire +4 more sources
Advanced Intelligent Discovery, EarlyView.This article implements a unified human digital twin framework that integrates cutting edge actuation, sensing, simulation, and bidirectional feedback capability. The approach includes integrating multimodal sensing, AI, and biomechanical simulation into one compact system.
Tajbeed Ahmed Chowdhury +4 more
wiley +1 more source
The Interoperability Challenge in DFT Workflows Across Implementations
Advanced Intelligent Discovery, EarlyView.Interoperability and cross‐validation remain major challenges in the computational materials science. In this work, we introduce a common input/output standard that enables internal translation across multiple workflow managers—AiiDA, PerQueue, Pipeline Pilot, and SimStack—while producing results in a unified schema.
Simon K. Steensen +13 more
wiley +1 more source
Analytical method (HPLC), validation used for identification and assay of the pharmaceutical active ingredient, Tylosin tartrate for veterinary use and its finite product Tilodem 50, hydrosoluble powder [PDF]
Medicamentul Veterinar, 2010 In SC DELOS IMPEX ’96 SRL the quality of the active pharmaceutical ingredient (API) for the finite product Tilodem 50 - hydrosoluble powder was acomkplished in the respect of last European Pharmacopoeia.The method for analysis used in this purpose was ...
Maria Neagu
doaj
Prednisone raw material characterization and formulation development
Brazilian Journal of Pharmaceutical Sciences, 2018 Solid dosage forms for oral use, particularly tablets, are the most highly used dosage forms in therapy because they are easily administered, have high productivity and relatively low cost and provide a more stable drug to form a semi-solid net. Numerous
Leonardo Henrique Toehwé +2 more
doaj +1 more source
Approaches to Drying Hydrated Active Pharmaceutical Ingredients (APIs).
, 2023 APPROVED
openaire +1 more source
Autonomous AI‐Driven Design for Skin Product Formulations
Advanced Intelligent Discovery, EarlyView.This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang +5 more
wiley +1 more source
Orbital: The Electronic Journal of ChemistryThe combination of different active substances in drug products is responsible for optimizing therapies and improving patient adherence. However, the development process of these formulations is highly challenging due to differences in the ...
Diana La Luna Bissetti Costa +7 more
doaj +1 more source
Advanced Intelligent Discovery, EarlyView.The hydration behavior of C3S in seawater‐relevant solutions is studied based on experiments, boundary nucleation and growth (BNG) modeling, and machine learning. The main ions included in seawater modify hydration mechanisms, with MgCl2 showing the strongest acceleration effect at the same concentration.
Yanjie Sun +6 more
wiley +1 more source
Excipients used in nano-technology assisted drug delivery systems
Journal of Excipients and Food Chemicals, 2016 The overall therapeutic benefit of an active pharmaceutical ingredient (API) is dependent on its potency and efficacy to deliver to the site of action.
Arvind Kumar Bansal
doaj